5 documents found, page 1 of 1
Exploring the potential protective effect of probiotics in obesity-induced colo...
Viana, Rejane; Rocha, Ana C.; Sousa, André P.; Ferreira, Diogo; Fernandes, Rúben; Almeida, Cátia; Pais, Patrick J.; Baylina, Pilar; Pereira, Ana CláudiaColorectal cancer (CRC) is the third most common cancer diagnosed today and the third leading cause of death among cancer types. CRC is one of the gastrointestinal tumors with obesity as the main extrinsic risk factor, since, according to authors, the meta-inflammation sustained by the excess adipose tissue can provide abundant circulating lipids, as well as hormones and metabolites crucial to tumor development...
Moving towards personalized medicine—The broad use of aptamers for targeted the...
Sousa, André P.; Rocha, Ana C.; Almeida, Cátia; Carneiro, Mariana C. C. G.; Pais, Patrick P.; Viana, Rejane; Fernandes, Rúben; Barata, PedroAptamers are short, single-stranded oligonucleotides synthesized in vitro from a randomized oligonucleotide library against a specific target. These molecules are capable of binding to a wide range of biological targets with high specificity and affinity. They present great advantages over antibodies with potential applications in research, diagnosis, and therapeutics. Specifically for tumors with late-stage id...
Moving towards personalized medicine - the broad use of aptamers for targeted t...
Sousa, André P.; Rocha, Ana C.; Almeida, Cátia; Carneiro, Mariana C. C. G.; Pais, Patrick P.; Viana, Rejane; Fernandes, Rúben Rodrigues; Barata, PedroAptamers are short, single-stranded oligonucleotides synthesized in vitro from a randomized oligonucleotide library against a specific target. These molecules are capable of binding to a wide range of biological targets with high specificity and affinity. They present great advantages over antibodies with potential applications in research, diagnosis, and therapeutics. Specifically for tumors with late-stage id...
The inner filter effects and their correction in fluorescence spectra of salt m...
Mendonça, Ana; Rocha, Ana C.; Duarte, Armando C.; Santos, Eduarda B. H.The inner filter effects in synchronous fluorescence spectra (δλ=60nm) of sedimentary humic substances from a salt marsh were studied. Accordingly to their type and the influence of plant colonization, these humic substances have different spectral features and the inner filter effects act in a different manner. The fluorescence spectra of the humic substances from sediments with colonizing plants have a protei...
Organic speciation of atmospheric particles in Alvão Natural Park (Portugal)
Alves, Célia Anjos; Gonçalves, Cátia; Mirante, Fátima; Nunes, Teresa; Evtyugina, Margarita; Sánchez de la Campa, Ana; Rocha, Ana C.PM(10) continental rural background aerosols were collected during a summer field campaign (August-September 2006) at Lamas de Olo in the upper zone of the Alvão Natural Park, a mountain region of northern Portugal. In addition to the determination of the carbonaceous content by a thermal-optical method, the organic speciation of aerosols was performed by gas chromatography-mass spectrometry in an effort to eva...