3 documents found, page 1 of 1
N-cinnamoylation of antimalarial classics: Quinacrine analogues with decreased ...
Gomes, A; Perez, B; Albuquerque, I; Machado, M; Prudencio, M; Nogueira, F; Teixeira, C; Gomes, PPlasmodium falciparum, the causative agent of the most lethal form of malaria, is becoming increasingly resistant to most available drugs. A convenient approach to combat parasite resistance is the development of analogues of classical antimalarial agents, appropriately modified in order to restore their relevance in antimalarial chemotherapy. Following this line of thought, the design, synthesis and in vitro e...
Markers of metabolic syndrome in obese children before and after 1-year lifesty...
Pedrosa, C; Oliveira, BMPM; Albuquerque, I; Simoes Pereira, C; Vaz de Almeida, MD; Correia, FExcess weight may be related to the development of adverse cardiometabolic risk factors in children. The aim of this study was to evaluate the effect of a lifestyle intervention program (nutrition and exercise counseling) on anthropometric parameters and metabolic syndrome (MS) components in Portuguese overweight/obese children. A total of 83 overweight/obese children aged 7-9 years were assigned to a 1-year in...
Serologic diagnosis of several infectious diseases.
Valente, C; Faria, M J; Trindade, L; Barros, M S; Vieira, A A; Albuquerque, I; Rodrigues, RSerological tests are, in some situations, the only method of diagnosis of some infectious diseases. The authors make a review of the literature about the most important tests used in the most common infectious diseases and also their interpretation. It is important to point out that serology should not be considered alone but compared to clinical manifestations presented by the patient. It is also necessary, i...