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Gaps and barriers to tuberculosis screening among anti-tumor necrosis factor pr...

Xerinda, S; Oliveira, O; Lucas, R; Fonseca, JE; Varela, P; Cotter, J; Duarte, R

Delegates from the Tuberculosis Committee of the Portuguese Pulmonology Society, the Portuguese Rheumatology Society, the Portuguese Dermatology and Venereology Society and the Portuguese Gastroenterology Society, have revised and updated, in 2012, their guidelines for the diagnosis and treatment of latent tuberculosis infection and active tuberculosis in patients that are candidates for therapy with biologic d...


Central/peripheral fat mass ratio is associated with increased risk of hyperten...

Freitas, P; Carvalho, D; Santos, AC; Madureira, AJ; Xerinda, S; Martinez, E; Pereira, J; Sarmento, A; Medina, JL

The data on the risk of hypertension in human immunodeficiency virus (HIV)-infected patients, particularly in those with lipodystrophy, are controversial. The authors assessed the impact of lipodystrophy on hypertension in a cohort of HIV-infected adults receiving combination antiretroviral therapy. This was a cross-sectional study in which lipodystrophy (clinically and fat mass ratio [FMR]-defined), blood pres...


Impact of Lipodystrophy on the prevalence and components of metabolic syndrome ...

Freitas, P; Carvalho, D; Souto, S; Santos, AC; Xerinda, S; Marques, R; Martinez, E; Sarmento, A; Medina, JL

Background: In HIV-infected patients, combination antiretroviral therapy (cART) is associated with clinical lipodystrophy (CL) and metabolic abnormalities (MA). This study aimed to evaluate the prevalence of the metabolic syndrome (MS) and its components, and to determine whether patients with or without CL had a different prevalence of MA.Methods: We evaluated 345 HIV-infected patients on cART using two differ...


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