7 documents found, page 1 of 1
Prevalência e perfil de resistência aos antimicrobianos de Staphylococcus aureu...
Bôtelho, Evillyn Xavier; Melo, Rosilma de Oliveira Araújo; Gusmão, Norma Buarque de; Ximenes, Rafael Matos; Sena, Kêsia Xisto da Fonseca Ribeiro deApesar de ser parte da microbiota humana normal, Staphylococcus aureus é um dos principais microrganismos patogênicos para o homem, causando desde infecções simples à potencialmente fatais. S. aureus é capaz de desenvolver fatores de resistência aos antimicrobianos, sendo motivo constante de preocupação e um grave problema de saúde pública. Este estudo analisou a prevalência de S. aureus em hospitais do Brasil,...
Schinus terebinthifolius leaf extract causes midgut damage, interfering with su...
Procópio, Thamara Figueiredo; Fernandes, Kenner Morais; Pontual, Emmanuel Viana; Ximenes, Rafael Matos; Oliveira, Aline Rafaella Cardoso deIn this study, a leaf extract from Schinus terebinthifolius was evaluated for effects on survival, development, and midgut of A. aegypti fourth instar larvae (L4), as well as for toxic effect on Artemia salina. Leaf extract was obtained using 0.15 M NaCl and evaluated for phytochemical composition and lectin activity. Early L4 larvae were incubated with the extract (0.3–1.35%, w/v) for 8 days, in presence or ab...
Antinociceptive effect of the essential oil obtained from the leaves of Croton ...
Nogueira, Lenise de Morais; Silva, Monalisa Ribeiro da; Santos, Simone Maria dos; Albuquerque, Julianna Ferreira Cavalcanti de; Ferraz, Igor CavalcantiCroton cordiifolius Baill. is a shrub known as “quebra-faca” and is used to treat inflammation, pain, wounds, and gastrointestinal disturbances in the semiarid region in the northeast of Brazil. In an ethnobotanical survey in the state of Pernambuco, “quebra-faca” use was cited in 33% of the interviews. Thus, we decided to evaluate the antinociceptive effects of the essential oil from C. cordiifolius (CcEO). Ch...
Synthesis and antimicrobial activities of 5-arylidene-thiazolidine-2,4-dione de...
Silva, Ivanildo Mangueira da; Silva Filho, João da; Santiago, Priscila Brandão Gomes da Silva; Egito, Micalyne Soares do; Souza, Carlos André deAntibiotic resistance is considered one of the world’s major public health concerns. The main cause of bacterial resistance is the improper and repeated use of antibiotics. To alleviate this problem, new chemical substances against microorganisms are being synthesized and tested. Thiazolidines are compounds having many pharmacological activities including antimicrobial activities. For this purpose some thiazoli...
Quercetin as an inhibitor of snake venom secretory phospholipase A2
Cotrim, Camila Aparecida; Buzzo de Oliveira, Simone Cristina; Diz Filho, Eduardo B. S.; Fonseca, Fabiana Vieira; Baldissera, Lineu; Antunes, EdsonMade available in DSpace on 2013-09-27T14:53:09Z (GMT). No. of bitstreams: 1 WOS000287004200002.pdf: 811833 bytes, checksum: 8b39287f53b1d7f23d5aa49a1c231297 (MD5) Previous issue date: 2011-01-15; Made available in DSpace on 2013-09-30T17:41:37Z (GMT). No. of bitstreams: 1 WOS000287004200002.pdf: 811833 bytes, checksum: 8b39287f53b1d7f23d5aa49a1c231297 (MD5) Previous issue date: 2011-01-15; Submitted by Vitor S...
Atividade antifosfolipásica A2 da harpalicina 2, uma isoflavona isolada de Harp...
Ximenes, Rafael MatosSecretory phospholipases A2 (sPLA2, EC 3.1.1.4) hydrolyses the sn-2 ester bond of phospholipids, releasing fatty acids and lysophospholipids. The expression of these enzymes is found to be elevated in many pathological conditions, such as rheumatoid arthritis, sepsis, atherosclerosis, and cancer. Moreover, sPLA2s are the main toxic components of some snake venoms, being the mainly responsible for the local tiss...
Avaliação da atividade da cabenegrina A-II frente às alterações bioquímicas e h...
Ximenes, Rafael MatosMedicinal plants against snakebite are widespread used in folk medicine in the world. This practice may be useful as a first treatment of snakebite victims, mainly in places where antivenom immunotherapy is not promptly available. Pterocarpans, especially the cabenegrins A-I and A-II, had their antiophidic activity proved by several experimental models. This work aimed to fix one efficient methodology to study ...