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The implementation of HFMEA in a primary care emergency service of the portugue...
Macedo, José Mário; Sá, Sara; Gestoso, Álvaro; Ramalho, Susana; Luís, Carla; Martins-Mendes, Daniela; Pereira, Ana Cláudia; Fernandes, RúbenOne of the main priorities for healthcare institutions is to provide better and more advanced services that contribute to prolonging the lives of those who seek their care, as well as improving their quality of life as long as it lasts. Both their patients and the professionals who work in those institutions need to feel protected against adverse effects that may affect them physically, mentally, or socially. A...
Unveiling the path to resilience: prioritizing mental health, sleep, and nutrit...
Ramalho, Susana; Martins-Mendes, Daniela; Macedo, José Mário; Barros, Carla; Luís, Carla; Sá, Sara; Gestoso, Álvaro; Pereira, Ana CláudiaThe COVID-19 pandemic has disrupted daily life, impacting relationships, work, and education. This has led to increased stress, anxiety, and depression, along with altered sleep patterns and eating behaviors. Quarantine and isolation have worsened mental health, especially in children and the elderly, due to the loss of activities and physical contact. Sleep disorders and negative dreams perpetuate poor sleep q...
Cutibacterium acnes dysbiosis: Alternative therapeutics for clinical application
Sá, Sara; Fernandes, Ruben; Gestoso, Álvaro; Macedo, José Mário; Martins-Mendes, Daniela; Pereira, Ana Cláudia; Baylina, PilarCutibacterium acnes (C. acnes) is a Gram-positive anaerobic facultative bacterium that is part of the human skin commensal microbiome. It colonizes various regions of the body, including the face, back, and chest. While typically a harmless commensal, under certain conditions, C. acnes can become pathogenic, leading to or promoting conditions such as acne vulgaris (AV), post-surgical infections, prostate cancer...
Virulence-linked mutations in rubredoxin reductase and glutaredoxin: impact on ...
Sá, Sara; Silva, Carina; Dias, Maria Clara; Veiga, Marlene; Lopes, Sofia; Fernandes, Ruben; Rocha, Ana Catarina; Pais, Patrick J.; Oliveira, MarcoPseudomonas aeruginosa (PAO1) is an opportunistic pathogen, lethal in immunocompromised individuals. The clinical management of PAO1 infections still depends deeply on antibiotic therapy. However, this therapy has been alarmingly overpowered by growing bacterial resistance mechanisms over the years. One of these bacterial mechanisms is quorum sensing (QS). QS is involved in the production of biofilm, rhamnolipi...