Made available in DSpace on 2021-06-25T10:59:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Aim: We aimed to develop methods to determine gabapentin (GAB) in biological samples using high-performance liquid chromatography (HPLC) with application in pharmacokinetic...
Made available in DSpace on 2019-10-06T16:14:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-04-01; Nifedipine, a known substrate to breast cancer resistance protein (ABCG2/BCRP), is used for the treatment of hypertension during breastfeeding. This study aimed to evaluate the effect of ABCG2 c.421C>A on nifedipine transfer to breast milk (BM) in hypertensive women. Nineteen hypertensive breastfeeding ...
Made available in DSpace on 2019-10-06T15:26:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-02-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); This study aimed to investigate the impact of diabetes treated or not with insulin in the enantioselective pharmacokinetics of tramadol (trans-T) and its phase 1 metabolit...
Made available in DSpace on 2018-12-11T17:30:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-07-01. Added 1 bitstream(s) on 2019-10-09T18:32:42Z : No. of bitstreams: 1 S1984-82502016000300517.pdf: 431977 bytes, checksum: b5aeaec5094612994a8757332bc4263a (MD5); The objective of this study was to identify drugs that received dose adjustments (DA) and pharmaceutical alternatives (PA) that avoid DA, and c...
The objective of this study was to identify drugs that received dose adjustments (DA) and pharmaceutical alternatives (PA) that avoid DA, and calculate the economic percentage of this replacement. A descriptive, observational and cross-sectional study was performed in a second level hospital. The pharmacy and nursing services was accompanied to identify the drugs that received DA and the compounding techniques....