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The prevalence of onchocerciasis in Africa and Yemen, 2000–2018: a geospatial a...

Schmidt, CA; Cromwell, EA; Hill, E; Donkers, KM; Schipp, MF; Johnson, KB; Pigott, DM; Abbas, J; Adekanmbi, V; Adetokunboh, OO; Ahmed, MB; Alanezi, FM

Background: Onchocerciasis is a disease caused by infection with Onchocerca volvulus, which is transmitted to humans via the bite of several species of black fly, and is responsible for permanent blindness or vision loss, as well as severe skin disease. Predominantly endemic in parts of Africa and Yemen, preventive chemotherapy with mass drug administration of ivermectin is the primary intervention recommended ...


The overlapping burden of the three leading causes of disability and death in s...

Reiner, RC; Welgan, CA; Troeger, CE; Baumann, MM; Weiss, DJ; Deshpande, A; Blacker, BF; Miller Petrie, MK; Earl, L; Bhatt, S; Abolhassani, H

Despite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa (SSA). The spatial burden of each of these diseases has been estimated subnationally across SSA, yet no prior analyses have examined the pattern of their com...


Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

Nogueira, RG; Qureshi, MM; Abdalkader, M; Martins, SO; Yamagami, H; Qiu, Z; Mansour, OY; Sathya, A; Czlonkowska, A; Tsivgoulis, G; Aguiar de Sousa, D

Objective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified ...


Subnational mapping of HIV incidence and mortality among individuals aged 15–49...

Sartorius, B; VanderHeide, JD; Yang, M; Goosmann, EA; Hon, J; Haeuser, E; Cork, MA; Perkins, S; Jahagirdar, D; Schaeffer, LE; Serfes, AL; LeGrand, KE

Background. High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. Methods. In this modelling study, we devel...


Anemia prevalence in women of reproductive age in low- and middle-income countr...

Kinyoki, D; Osgood-Zimmerman, AE; Bhattacharjee, NV; Schaeffer, LE; Lazzar-Atwood, A; Lu, D; Ewald, SB; Donkers, KM; Letourneau, ID; Collison, M

Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Addi...


Mapping inequalities in exclusive breastfeeding in low- and middle-income count...

Bhattacharjee, NV; Schaeffer, LE; Hay, SI; Lu, D; Schipp, MF; Lazzar-Atwood, A; Donkers, KM; Abady, GG; Abd-Allah, F; Abdelalim, A; Abebo, ZH

Exclusive breastfeeding (EBF)-giving infants only breast-milk for the first 6 months of life-is a component of optimal breastfeeding practices effective in preventing child morbidity and mortality. EBF practices are known to vary by population and comparable subnational estimates of prevalence and progress across low- and middle-income countries (LMICs) are required for planning policy and interventions. Here w...


Mapping routine measles vaccination in low- and middle-income countries

Sbarra, AN; Rolfe, S; Nguyen, JQ; Earl, L; Galles, NC; Marks, A; Abbas, KM; Abbasi-Kangevari, M; Abbastabar, H; Abd-Allah, F; Abdelalim, A; Abdollahi, M


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