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Identification of crotasin, a crotamine-related gene of Crotalus durissus terri...

Rádis-Baptista, Gandhi; Kubob, T.; Oguiura, Nancy; Prieto da Silva, A.R.B.; Hayashid, M.A.F.; Oliveirae, E.B.; Yamane, T.

Crotamine is a cationic peptide (4.9 kDa, pI 9.5) of South American rattlesnake, Crotalus durissus terrificus’ venom. Its presence varies according to the subspecies or the geographical locality of a given species. At the genomic level, we observed the presence of 1.8 kb gene, Crt-p1, in crotamine-positive specimens and its absence in crotamine-negative ones. In this work, we described a crotamine-related 2.5 k...

Date: 2021   |   Origin: Oasisbr

Crotacetin, a novel snake venom c-type lectin, is homolog of convulxin

Rádis-Baptista, Gandhi; Moreno, F. B. M. B.; Nogueira, L. L.; Martins, A. M. C.; Tomaya, D. O; Tomaya, M. H; Azevedo Júnior, W. F.; Cavada, B. S.

Snake venom (sv) C-type lectins encompass a group of hemorrhagic toxins, which are able to interfere with hemostasis. They share significant similarity in their primary structures with C-type lectins of other animals, and also present a conserved carbohydrate recognition domain (CRD). A very well studied sv C-type lectin is the heterodimeric toxin, convulxin (CVX), from the venoms of South American rattlesnakes...

Date: 2021   |   Origin: Oasisbr

Nucleotide sequence of crotamine isoform precursors from a single South America...

Rádis-Baptista, Gandhi; Oguiura, Nancy; Hayashi, M.A.F.; Camargoc, M.E.; Gregod, K.F.; Oliveira, E.B.; Yamane, T.

A cDNA phage library was constructed from venom glands of a single adult specimen of crotamine-plus Crotalus durissus terri®cus (South American rattlesnake) captured in a known region. Fifteen crotamine positive clones were isolated using a PCR-based screening protocol and sequenced. These complete cDNAs clones were grouped for maximal alignment into six distinct nucleotide sequences. The crotamine cDNAs, with ...

Date: 2021   |   Origin: Oasisbr

Crotacetin, a novel snake venom C-type lectin, is homolog of convulxin

Rádis-baptista, G.; Moreno, F. B. M. B.; Nogueira, L. L.; Martins, A. M. C.; Toyama, D. O.; Toyama, M. H. [UNESP]; Azevedo Jr, W. F. [UNESP]

Made available in DSpace on 2021-07-14T10:50:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2005-12. Added 1 bitstream(s) on 2021-07-14T11:39:11Z : No. of bitstreams: 1 S1678-91992005000400013.pdf: 827726 bytes, checksum: 65adf78968e48f1e78beea14818e20a7 (MD5); Snake venom (sv) C-type lectins encompass a group of hemorrhagic toxins, which are able to interfere with hemostasis. They share significant simil...

Date: 2021   |   Origin: Oasisbr

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