3 documents found, page 1 of 1
Bilateral evaluation of the hand and wrist in untreated early Inflammatory Arth...
Navalho, Márcio; Resende, Catarina; Rodrigues, Ana Maria; Pereira da Silva, José Alberto; Fonseca, João Eurico; Campos, Jorge; Canhao, HelenaMethods: Forty-five patients (40 women, 5 men; mean age 45.6 yrs) with untreated recent-onset polyarthritis participated in this prospective study and were examined using an US and MRI approach including both wrists and hands. After a followup of 12 months, patients were classified as having RA if they fulfilled the criteria for RA. The proportion of synovitis identified by US and MRI for each joint and tendon ...
BAFF and TACI gene expression are increased in patients with untreated very ear...
Moura, Rita; Canhao, Helena; Polido Pereira, Joaquim; Rodrigues, Ana Maria; Navalho, Márcio; Mourão, Ana F.; Resende, CatarinaObjective: B cells play important roles in rheumatoid arthritis (RA). Given the beneficial effect of B cell depletion therapy in RA as well as the observed alterations in B cell subpopulations in this disease, we evaluated whether changes in the expression of genes related to B cell survival and activation were already present in patients with untreated very early RA (VERA; < 6 weeks of disease duration). Metho...
Endometriose – epidemiologia, fisiopatologia e revisão clínica e radiológica
Campos, Cláudia; Navalho, Márcio; Cunha, Teresa MargaridaA endometriose é definida como a presença de tecido endometrial em localização ectópica. Ocorre predominantemente em mulheres em idade fértil, apresentando-se clinicamente com algia pélvica, dispareunia e infertilidade. As localizações mais habituais são o ovário, o miométrio (adenomiose) e o torus uterino, podendo surgir em outros órgãos, como a bexiga, o intestino ou pulmão. São consideradas actualmente três ...