13 documents found, page 1 of 2

Clonally Related Chronic Myelomonocytic Leukemia and Erdheim-Chester Disease wi...

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Impact of novel clean label ham formulations on the human gut microbiota

Introduction: The influence of diet on the human gut microbiota has been the subject of much debate, particularly in relation to innovative products that are still considered novel. Dietary habits have a fundamental impact on the human gut microbiota, which explains the variations observed between individuals and over the course of a lifetime. The aim of this study was to evaluate the effect of four clean label...

Rhamnolipids: A biosurfactant for the development of lipid-based nanosystems fo...

Biosurfactants (surfactants synthesized by microorganisms) are produced by microorganisms and are suitable for use in different areas. Among biosurfactants, rhamnolipids are the most studied and popular, attracting scientists, and industries interest. Due to their unique characteristics, the rhamnolipids have been used as synthetic surfactants alternatives and explored in food applications. Besides the producti...

Rhamnolipids-based nanostructured lipid carriers: Effect of lipid phase on phys...

In this work rhamnolipids were evaluated as surfactants for the production of nanostructured lipid carriers (NLCs). NLCs were produced by melt-emulsification using ultra-homogenisation followed by ultrasonication and different ratios of medium-chain-triglycerides and glycerol monostearate (lipid phase) were tested. NLCs presented sizes and polydispersity index values ranged between 97 and 120 nm and 0.200.26, r...

Phototherapy as a First Line Treatment for Mycosis Fungoides: A 10-year Retrosp...

Introduction: Phototherapy, particularly psoralen plus ultraviolet A (PUVA) and narrowband ultraviolet B (nbUVB), is a mainstay in the treatment of Mycosis Fungoides (MF). Methods: We analyzed outcomes of MF patients treated for the first time with either PUVA or nbUVB at the Photodermatology Unit, in the Department of Dermatology of Centro Hospitalar Universitário do Porto, from 2007 to 2017. The primary outco...

A Single Cutaneous Ulcer in a Healthy Adolescent

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Multiple telangiectasias in a child

Formation and stabilization of nanostructured-lipid carriers using biosurfactan...

Liposoluble vitamins exhibit poor solubility in aqueous mediums and are very sensitive and unstable when exposed to inadequate conditions (e.g. temperature and pH). With that in mind, it is important to preserve the properties of these molecules and improve their biological efficiency. Nanoencapsulation can be an alternative and the nanostructuredlipid carriers (NLC’s) are presented to be a good alternative for...

Predicting prognosis in patients with advanced cancer: A prospective study

Prognosis is one of the most challenging questions with which physicians are confronted. Accuracy in the prediction of survival is necessary for clinical, ethical, and organizational reasons.

Biosimilar Agents for Psoriasis Treatment: The Perspective of Portuguese Patients

Introduction: Biosimilars are highly similar copies of previously approved original biologic medicines. Their introduction on the market may yield cost reduction. The aim of this study was to evaluate the perspectives of psoriasis patients on biosimilar medications.Materials and Methods: We conducted a 14 questions survey of psoriasis patients receiving biological therapy and followed-up in a dermatology depart...