Background Staphylococcus aureus and Staphylococcus pseudintermedius are responsible for skin and soft-tissue infections (SSTIs) in companion animals and are increasingly associated with antimicrobial resistance (AMR). Chlorhexidine (CHX) is one of the most used and recommended antisseptic in the treatment of SSTIs in these animals. This study analyzed the effectiveness, at different conditions, of CHX against ...