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Haptoglobin gene subtypes in three Brazilian population groups of different eth...
Vilela, Ana Luísa Miranda; Akimoto, Arthur Kenji; Alves, Penha Cristina Zaidan; Hiragi, Cássia de Oliveira; Penalva, Guilherme C.; Oliveira, Silviene F.Haptoglobin is a plasma hemoglobin-binding protein that limits iron loss during normal erythrocyte turnover and hemolysis, thereby preventing oxidative damage mediated by iron excess in the circulation. Haptoglobin polymorphism in humans, characterized by the Hp*1 and Hp*2 alleles, results in distinct phenotypes known as Hp1-1, Hp2-1 and Hp2-2, whose frequencies vary according to the ethnic origin of the popula...
Data: 2018
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Origem: Oasisbr