4 documents found, page 1 of 1
Inhalation of dimethyl fumarate-encapsulated solid lipid nanoparticles attenuat...
Pinto, Barbara Fernandes; Ribeiro, Lorena Natasha Brito; Da Silva, Gisela Bevilacqua Rolfsen Ferreira [UNESP]; Freitas, Camila Simoes; Kraemer, LucasMade available in DSpace on 2022-04-29T08:38:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Rationale: The FDA-approved Dimethyl Fumarate (DMF) as an oral drug for Multiple Sclerosis (MS) treatment based on its immunomodulatory activities. However, it also caused severe adverse effects mainly related to the gastrointestinal system. Objective: Investigated the potential effects of solid lipid n...
Chronic ethanol consumption compromises neutrophil function in acute pulmonary ...
Soriani, Frederico Marianetti
Brazilian green propolis modulates inflammation, angiogenesis and fibrogenesis ...
Lima, Luiza Dias da Cunha; Andrade, Silvia Passos de; Campos, Paula Peixoto; Barcelos, Luciola da Silva; Soriani, Frederico MarianettiBackground: Chronic inflammatory processes in the peritoneal cavity develop as a result of ischemia, foreign body reaction, and trauma. Brazilian green propolis, a beeswax product, has been shown to exhibit multiple actions on inflammation and tissue repair. Our aim was to investigate the effects of this natural product on the inflammatory, angiogenic, and fibrogenic components of the peritoneal fibroproliferat...
The conserved and divergent roles of carbonic anhydrases in the filamentous fun...
Han, Kap-Hoon; Chun, Yoon-Hee; Figueiredo, Bárbara de Castro Pimentel; Soriani, Frederico Marianetti; Savoldi, Marcela; Almeida, Agostinho João RamalhoCarbon dioxide (CO(2)) and its hydration product bicarbonate (HCO(3)(-)) are essential molecules in various physiological processes of all living organisms. The reversible interconversion between CO(2) and HCO(3)(-) is in equilibrium. This reaction is slow without catalyst, but can be rapidly facilitated by Zn(2+)-metalloenzymes named carbonic anhydrases (CAs). To gain an insight into the function of multiple c...