23 documents found, page 1 of 3
Genome-wide DNA (hydroxy) methylation reveals the individual epigenetic landsca...
Ferreira, Rogério S.; Assis, Rahyza I. F.; Feltran, Geórgia da S. [UNESP]; do Rosário Palma, Iasmin Caroline; Françoso, Beatriz G.Made available in DSpace on 2022-04-28T19:43:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Background: Mesenchymal cells’ biology has been an important investigative tool to maximize bone regeneration through tissue engineering. Here we used mesenchymal cells from periodontal ligament (PDLCs) with high (h-) and low (l-) osteogenic potential, isolated from different donors, to investigate the ...
The molecular pathway triggered by zirconia in endothelial cells involves epige...
da C. Fernandes, Célio Júnior [UNESP]; da Silva, Rodrigo A.; Fretes Wood, Patrícia [UNESP]; Teixeira, Suélen Aparecida [UNESP]; Bezerra, Fábio [UNESP]Made available in DSpace on 2022-04-29T08:32:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The requirement to achieve natural looking restorations is one of the most challenging aspects in dentistry. Although zirconia has provided new opportunities for achieving superior aesthetics and physicochemical outcomes, very little ...
Bioactivity of the Protein Hydrolysates Obtained from the Most Abundant Crustac...
Camargo, Tavani R. [UNESP]; Mantoan, Paulo [UNESP]; Ramos, Patrícia; Monserrat, José M.; Prentice, Carlos; Fernandes, Célio C. [UNESP]Made available in DSpace on 2022-04-29T08:36:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; The animals from bycatch of the shrimp fisheries can be a source of natural products and bioactive compounds. Thus, the present study aimed to evaluate the bioactivity of protein hydrolysates prepared from the two most abundant crabs from the bycatch of shrimp fisheries in Brazil (Callinectes ornatus an...
The Impact of Bioactive Surfaces in the Early Stages of Osseointegration: An in...
Da Silva, Rodrigo A. [UNESP]; Da Silva Feltran, Geórgia [UNESP]; Ferreira, Marcel Rodrigues [UNESP]; Wood, Patrícia Fretes [UNESP]Made available in DSpace on 2021-06-25T10:13:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; There is an increased effort on developing novel and active surfaces in order to accelerate their osteointegration, such as nanosized crystalline hydroxyapatite coating (HAnano®). To better understand the biological behavior of osteoblasts grown on HAnano® surface, the set of data was compared with SLAc...
Biological activities of the protein hydrolysate obtained from two fishes commo...
Rocha Camargo, Tavani [UNESP]; Ramos, Patrícia; Monserrat, José M.; Prentice, Carlos; Fernandes, Célio J.C. [UNESP]; Zambuzzi, Willian F. [UNESP]Made available in DSpace on 2021-06-25T10:36:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-16; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Shrimp trawling is an important socio-economic activity; however, the bycatch can be problematic to the environment. Thus, the present study investigated potential uses of...
Non-coding RNAs repressive role in post-transcriptional processing of RUNX2 dur...
Assis, Rahyza I.F.; Feltran, Geórgia da S. [UNESP]; Silva, Maria Eduarda Salomão; Palma, Iasmin Caroline do Rosário; Rovai, Emanuel SilvaMade available in DSpace on 2021-06-25T10:16:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Mesenchymal stem cells are candidates for therapeutic strategies in periodontal repair due to their osteogenic potential. In this study, we identified epigenetic markers during osteogenic differentiation, taking advantage of the indiv...
Immobilization of Paclitaxel on Hydroxyapatite for Breast Cancer Investigations
Martins, Murillo L.; Pinto, Thais S. [UNESP]; Gomes, Anderson M. [UNESP]; Parra, João P. R. L. L. [UNESP]; Franchi, Gilberto C.Made available in DSpace on 2020-12-12T02:19:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-08-04; A simple method for immobilization of the chemotherapy drug paclitaxel (PTX) on hydroxyapatite nanoparticles (n-HAP) using the biopolymer chitosan as a trapping agent is described focusing on applications involving breast cancer cells. n-HAP with two distinct crystallinity profiles were used: with predo...
GSVA score reveals molecular signatures from transcriptomes for biomaterials co...
Ferreira, Marcel R. [UNESP]; Santos, Gerson A. [UNESP]; Biagi, Carlos A.; Silva Junior, Wilson A.; Zambuzzi, Willian F. [UNESP]Made available in DSpace on 2020-12-12T02:22:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Two in silico methodologies were implemented to reveal the molecular signatures of inorganic hydroxyapatite and β-TCP materials from a transcriptome database to compare biomaterials. To test this new methodology, we choose the array E-MTAB-7219, which contains the transcription profile of osteoblastic c...
The role of apoptosis associated speck-like protein containing a caspase-1 recr...
Sartoretto, Suelen C.; Calasans-Maia, Monica D.; Alves, Adriana T.N.N.; Resende, Rodrigo F.B.; da Costa Fernandes, Célio Junior [UNESP]Made available in DSpace on 2020-12-12T02:02:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ); The apoptosis-associated Speck-lik...
LncRNA HOTAIR is a novel endothelial mechanosensitive gene
da Silva, Rodrigo A. [UNESP]; Ferreira, Marcel Rodrigues [UNESP]; Gomes, Anderson Moreira [UNESP]; Zambuzzi, Willian F. [UNESP]Made available in DSpace on 2020-12-12T01:44:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); To better address whether the long noncoding RNAs (lncRNAs) HOTAIR and HOTTIP are mechanosensitive genes, they were investigated in differentially challenged endothelial c...