Aging and poor sleep quality are associated with altered brain dynamics, yet current electroencephalography (EEG) analyses often overlook regional complexity. This study addresses this gap by introducing a novel integration of intra- and inter-regional complexity analysis using multivariate multiscale dispersion entropy (mvMDE) from awake resting-state EEG for the first time. Moreover, assessing both intra- and...
BACKGROUND: Good sleep quality is essential for both physiological and mental health. It helps in clearing TAU and beta-amyloid aggregates and consolidating memory, key processes in delaying dementia. Poor sleep is linked to reduced cognitive flexibility in daily life, likely due to decreased brain complexity, reflecting a reduced range of adaptive spatiotemporal brain dynamics. This study introduces a novel ap...