Made available in DSpace on 2022-04-28T19:46:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Ministério da Saúde; We describe the circulation of Saint Louis encephalitis virus (SLEV) in two Brazilian States during outbreaks of Dengue and Zika viruses. We detected the virus in a patient from Araraquara, State of São Paulo, and...
Made available in DSpace on 2022-04-29T08:46:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-02; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Friedelin, a pentacyclic triterpene found in the leaves of the Celastraceae species, demon-strates numerous biological activities and is a precursor of quinonemethide trite...
Made available in DSpace on 2019-10-05T12:40:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-02-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Due to their unique and versatile biochemical properties, ruthenium-based compounds have emerged as pr...
Made available in DSpace on 2018-12-11T17:36:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-01. Added 1 bitstream(s) on 2019-10-09T18:33:08Z : No. of bitstreams: 1 S0103-50532018000501105.pdf: 2907602 bytes, checksum: ef8123c16f0caba93af7dd13a547df64 (MD5); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Département Caractérisation et Élaboration des Produits Issus de l’Agriculture,...
Made available in DSpace on 2018-12-11T17:36:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-01-01; Triterpenes are interesting compounds because they play an important role in cell homeostasis and a wide variety exhibiting defense functions is produced by plant secondary metabolism. Those same plant secondary metabolites also exhibit biological properties with promising therapeutic potential as anti-...
Made available in DSpace on 2018-12-11T17:21:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-08-01; A complexity of pathway expression in yeast compared to prokaryotes is the need for separate promoters and terminators for each gene expressed. Single transcript expression and separated protein production is possible via the use of 2A viral peptides, but detailed characterization to assess their suitab...
Made available in DSpace on 2018-12-11T17:23:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-11-22; Among the biologically active triterpenes, friedelin has the most-rearranged structure produced by the oxidosqualene cyclases and is the only one containing a cetonic group. In this study, we cloned and functionally characterized friedelin synthase and one cycloartenol synthase from Maytenus ilicifolia ...
Made available in DSpace on 2018-12-11T17:04:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-04-01; National Institute of General Medical Sciences; eIF5A is the only protein known to contain the essential and unique amino acid residue hypusine. eIF5A functions in both translation initiation due to its stimulation of methionyl-puromycin synthesis and translation elongation, being highly required for pe...
Made available in DSpace on 2018-12-11T17:04:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-10-01; The translation elongation factor eIF5A is conserved through evolution and is necessary to rescue the ribosome during translation elongation of polyproline-containing proteins. Although the site of eIF5A binding to the ribosome is known, no systematic analysis has been performed so far to determine the ...