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Towards a machine learning framework for predicting MicroRNAs involved in Candi...

Miranda, Tiago; Ferraz, Filipa; Henriques, Mariana; Silva, Sónia Carina; Gonçalves, Bruna Fernandes

Infections caused by Candida species present significant clinical challenges, leading to high morbidity and mortality rates. Emerging research suggests that microRNAs (miRNAs) may serve as valuable biomarkers for diagnosing and treating candidiasis, although the field is still developing. The scarcity of reported miRNAs associated with candidiasis stems from the complexities and costs of screening numerous pote...


A multidisciplinary engineering-based approach for tunnelling strengthening wit...

Barros, Joaquim; Costelha, Hugo; Bento, David; Brites, Nelson; Luís, Rui; Patrício, Hugo; Cunha, Vítor M.C.F.; Bento, Luís; Miranda, Tiago

This paper describes the relevant research activities that are being carried out on the development of a novel shotcrete technology capable of applying, autonomously and in real time, fibre reinforced shotcrete (FRS) with tailored properties regarding the optimum structural strengthening of railway tunnels (RT). This technique allows to apply fibre reinforced concrete (FRC) of strain softening (SSFRC) and strai...

Date: 2024   |   Origin: IC-online

A multidisciplinary engineering-based approach for tunnelling strengthening wit...

Barros, Joaquim A. O.; Costelha, Hugo; Bento, David; Brites, Nelson; Luís, Rui; Patrício, Hugo; Cunha, Vitor; Bento, Luís; Miranda, Tiago; Coelho, Paulo

This paper describes the relevant research activities that are being carried out on the development of a novel shotcrete technology capable of applying, autonomously and in real time, fibre reinforced shotcrete (FRS) with tailored properties regarding the optimum structural strengthening of railway tunnels (RT). This technique allows to apply fibre reinforced concrete (FRC) of strain softening (SSFRC) and strai...


Primary health care appointments and hospital stay: an impact analysis

Lopes, Joana; Miranda, Tiago; Sousa, Regina; Machado, José Manuel

The study of avoidable hospitalizations has gained international prom-inence due to its potential to assess the performance of healthcare systems. In Canada and Spain, these hospitalizations are analyzed through Ambulatory Care Sensitive Conditions (ACSC), indicating situations that could have been pre-vented or treated without hospitalization. In Portugal, this concept is represented by the term ICSCSP, focusi...


Mechanical behavior of a mine tailing stabilized with a sustainable binder

Manaviparast, Hamid Reza; Pinheiro, João; Najafi, Elmira Khaksar; Abreu, Cláudia; Araújo, Nuno; Cristelo, Nuno; Miranda, Tiago

Mining is a primary sector for the national economy of many countries, but exploiting these natural resources causes negative impacts on the environment. Tailings produced during mining, called mine tailings, have to be disposed of, and for that purpose, they are often mixed with Portland cement to control environmental toxicity and improve their mechanical properties. However, the high environmental impacts of...


Numerical analysis of the flow field and cross section design implications in a...

Maslov, Dmytro; Pereira, Eduardo; Duarte, Duarte; Miranda, Tiago; Ferreira, Vasco; Tieppo, Marcos; Cruz, Fábio; Johnson, Jessica

Nowadays, multifunctional artificial reefs are integrated in coastal areas all around the world. The design of such structures is currently complex and subjective. In this context, it is essential to improve overall design approaches to more effectively relate artificial reef geometry, function and optimal performance to specific deployment sites. Part of the solution to this challenge may lie in the use of in ...


Colaboração premiada: uma análise crítica de sua eficácia na busca da verdade real

Miranda, Tiago

Este trabalho tem como objetivo analisar os aspectos dos acordos de colaboração premiada frente à constituição, diante da forma como é obtida a prova e o meio que é utilizada no decorrer do processo penal. Nessa perspectiva, a colaboração premiada é um instituto onde as partes envolvidas na relação processual podem negociar os termos do referido acordo. O presente trabalho tem como foco a validade e eficácia da...

Date: 2022   |   Origin: Oasisbr

Submarine cables as precursors of persistent systems for large scale oceans mon...

Tieppo, Marcos; Pereira, Eduardo; Garcia, Laura Gonzalez; Rolim, Margarida; Castanho, Emanuel; Matos, Anibal; Silva, António; Ferreira, Bruno

Long-term and reliable marine ecosystems monitoring is essential to address current environmental issues, including climate change and biodiversity threats. The existing oceans monitoring systems show clear data gaps, particularly when considering characteristics such as depth coverage or measured variables in deep and open seas. Over the last decades, the number of fixed and mobile platforms for in situ ocean ...


Stabilisation of a plastic soil with alkali activated cements developed from in...

Cristelo, Nuno; Rivera, Jhonathan; Miranda, Tiago; Fernández-Jiménez, Ana

The development of alternative materials for the construction industry, based on different types of waste, is gaining significant importance in recent years. This is mostly due to the need to increase sustainability of this heavily polluting activity, thus mitigating the dependence on, for instance, Portland cement. The present paper is related to the development of an alkaline activated cement (AAC) exclusivel...


Unsaturated response of clayey soils stabilised with alkaline cements

Araújo, Nuno; Corrêa-Silva, Manuela; Miranda, Tiago; Topa Gomes, António; Castro, Fernando; Teixeira, Tiago; Cristelo, Nuno

The influence of suction on the mechanical behaviour of unsaturated chemically stabilised soils is still mostly unknown and unquantified. This is also motivated by the difficulties associated with the experimental procedure required to fully characterise the unsaturated response of the soil, including its direct influence on traditional strength tests. The present paper presents the soil water retention curves ...


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