2 documents found, page 1 of 1
Editorial: Herbal medical products and natural products targeting aging and age...
Ullah, Hammad; Khan, Haroon; Prieto Lage, Miguel A.; Daglia, MariaThe population aged ≥60 years is growing worldwide. The World Health Organization (WHO) reported that the elderly population is expected to increase from 1 billion in 2020 to 1.4 billion in 2030 and 2.1 billion in 2050 (World Health Organization, 2022). This increase in life expectancy around the globe is accompanied with the enhancing frequency of agingassociated disorders, mainly due to the deterioration of m...
Targeting NF-κB signaling pathway in cancer by dietary polyphenols
Khan, Haroon; Ullah, Hammad; Castilho, Paula Cristina Machado Ferreira; Gomila, Antoni Sureda; D'Onofrio, Grazia; Filosa, Rosanna; Wang, FangBeing a transcription factor, NF-κB regulates gene expressions involving cell survival and proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a central role in the development of inflammation and cancer. Thus, the down-regulation of NF-κB may be an exciting target in prevention and treatment of cancer. NF-κB could act as a tumor activator or tumor suppressant decided by ...