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Coma in adult cerebral venous thrombosis: the BEAST study

Ranjan, Redoy; Ken‐Dror, Gie; Martinelli, Ida; Grandone, Elvira; Hiltunen, Sini; Lindgren, Erik; Margaglione, Maurizio; Duchez, Veronique Le Cam

Background and purpose: Coma is an independent predictor of poor clinical outcomes in cerebral venous thrombosis (CVT). We aimed to describe the association of age, sex, and radiological characteristics of adult coma patients with CVT. Methods: We used data from the international, multicentre prospective observational BEAST (Biorepository to Establish the Aetiology of Sinovenous Thrombosis) study. Only positive...


Obesity and the risk of cryptogenic ischemic stroke in young adults

Jaakonmäki, Nina; Zedde, Marialuisa; Sarkanen, Tomi; Martinez-Majander, Nicolas; Tuohinen, Suvi; Sinisalo, Juha; Ryödi, Essi; Autere, Jaana

Objectives: We examined the association between obesity and early-onset cryptogenic ischemic stroke (CIS) and whether fat distribution or sex altered this association. Materials and methods: This prospective, multi-center, case-control study included 345 patients, aged 18-49 years, with first-ever, acute CIS. The control group included 345 age- and sex-matched stroke-free individuals. We measured height, weight...


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