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Dairying, diseases and the evolution of lactase persistence in Europe

Evershed, Richard P.; Davey Smith, George; Roffet-Salque, Mélanie; Timpson, Adrian; Diekmann, Yoan; Lyon, Matthew S.; Cramp, Lucy J. E.

In European and many African, Middle Eastern and southern Asian populations, lactase persistence (LP) is the most strongly selected monogenic trait to have evolved over the past 10,000 years(1). Although the selection of LP and the consumption of prehistoric milk must be linked, considerable uncertainty remains concerning their spatiotemporal configuration and specific interactions(2,3). Here we provide detaile...


Ancient pigs reveal a near-complete genomic turnover following their introducti...

Frantz, Laurent A. F.; Haile, James; Lin, Audrey T.; Scheu, Amelie; Geörg, Christina; Benecke, Norbert; Alexander, Michelle; Linderholm, Anna

Archaeological evidence indicates that pig domestication had begun by ∼10,500 y before the present (BP) in the Near East, and mitochondrial DNA (mtDNA) suggests that pigs arrived in Europe alongside farmers ∼8,500 y BP. A few thousand years after the introduction of Near Eastern pigs into Europe, however, their characteristic mtDNA signature disappeared and was replaced by haplotypes associated with European wi...


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