4 documents found, page 1 of 1
Rice bran modulates renal disease risk factors in animals submitted to high sug...
Siqueira,Juliana Silva; Francisqueti-Ferron,Fabiane Valentini; Garcia,Jéssica Leite; Silva,Carol Cristina Vágula de Almeida; Costa,Mariane RóveroAbstract Introduction: Obesity, diabetes, and hypertension are common risk factors for chronic kidney disease (CKD). CKD arises due to many pathological insults, including inflammation and oxidative stress, which affect renal function and destroy nephrons. Rice bran (RB) is rich in vitamins and minerals, and contains significant amount of antioxidants. The aim of this study was to evaluate the preventive effect ...
Gamma-oryzanol reduces renal inflammation and oxidative stress by modulating AG...
Francisqueti-Ferron,Fabiane Valentini; Ferron,Artur Junio Togneri; Altomare,Alessandra; Garcia,Jéssica Leite; Moreto,Fernando; Ferreira,Ana Lúcia A.Abstract Introduction: The receptor for AGEs (RAGE) is a multiligand member of the immunoglobulin superfamily of cell surface receptors expressed in many organs, among them, the kidneys. When activated, RAGE leads to a sequence of signaling that results in inflammation and oxidative stress, both involved in kidney disease pathogenesis. Gamma-oryzanol (γOz) comprises a mixture of ferulic acid (FA) esters and phy...
The role of oxidative stress on the pathophysiology of metabolic syndrome
Francisqueti,Fabiane Valentini; Chiaverini,Lidiana Camargo Talon; Santos,Klinsmann Carolo dos; Minatel,Igor Otávio; Ronchi,Carolina BerchieriSummary Metabolic syndrome (MetS) has a high prevalence around the world. Considering the components used to classify MetS, it is clear that it is closely related to obesity. These two conditions begin with an increase in abdominal adipose tissue, which is metabolically more active, containing a greater amount of resident macrophages compared to other fat deposits. Abdominal adiposity promotes inflammation and ...
Inflamação renal, alterações metabólicas e oxidativas após 6 semanas de dieta d...
Navarro,Maria Eugênia Lopes; Santos,Klinsmann Carolo dos; Nascimento,André Ferreira do; Francisqueti,Fabiane Valentini; Minatel,Igor OtávioResumo Introdução: A obesidade é uma doença em que a inflamação está inteiramente envolvida e pode causar insuficiência renal. Objetivo: Avaliar a influência da exposição a curto prazo de uma dieta de cafeteria sobre a inflamação no tecido renal e a formação de produtos de glicação avançada (AGEs) no plasma de rato. Métodos: Ratos Wistar machos (10 semanas de idade, pesando 350 g) foram designados para receber ...