6 documents found, page 1 of 1
An oral nanomedicine elicits in situ vaccination effect against colorectal cancer
Zu, Menghang; Ma, Ya; Zhang, Jun; Sun, Jianfeng; Shahbazi, Mohammad-Ali; Pan, Guoqing; Reis, R. L.; Kundu, Subhas C; Liu, Jinyao; Xiao, BoOral administration is the most preferred approach for treating colon diseases, and in situ vaccination has emerged as a promising cancer therapeutic strategy. However, the lack of effective drug delivery platforms hampered the application of in situ vaccination strategy in oral treatment of colorectal cancer (CRC). Here, we construct an oral coreâ shell nanomedicine by preparing a silk fibroin-based dual s...
DAO1 catalyzes temporal and tissue-specific oxidative inactivation of auxin in ...
Zhang, Jun; Lin, Jinshan Ella; Harris, Chinchu; Pereira, Fernanda Campos Mastrotti [UNESP]; Wu, Fan; Blakeslee, Joshua J.; Peer, Wendy AnnMade available in DSpace on 2022-04-28T19:04:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-09-27; Tight homeostatic regulation of the phytohormone auxin [indole-3-acetic acid (IAA)] is essential to plant growth. Auxin biosynthetic pathways and the processes that inactivate auxin by conjugation to amino acids and sugars have been thoroughly characterized. However, the enzyme that catalyzes oxidation ...
Trends and projections of caesarean section rates: global and regional estimates
Zhang, Jun
Global impact of COVID-19 on stroke care and IV thrombolysis
Nogueira, Raul G.; Qureshi, Muhammad M.; Abdalkader, Mohamad; Martins, Sheila Ouriques; Yamagami, Hiroshi; Qiu, Zhongming; Mansour, Ossama YassinObjective: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. Methods: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified ...
Searching for the optimal rate of medically necessary cesarean delivery
Zhang, Jun
Intraoperative fluid management in open gastrointestinal surgery: goal-directed...
Zhang, Jun; Qiao, Hui; He, Zhiyong; Wang, Yun; Che, Xuehua; Liang, WeiminOBJECTIVE: The optimal strategy for fluid management during gastrointestinal surgery remains unclear. Minimizing the variation in arterial pulse pressure, which is induced by mechanical ventilation, is a potential strategy to improve postoperative outcomes. We tested this hypothesis in a prospective, randomized study with lactated Ringer's solution and 6% hydroxyethyl starch solution. METHOD: A total of 60 pati...