8 documents found, page 1 of 1
White and red LEDs as two-phase batch for cyanobacterial pigments production
Pagels, F; Lopes, G; Vasconcelos, V; Guedes, A.C.Carotenoids and phycobiliproteins have a high economic value, due to their wide range of biological and industrial applications. The implementation of strategies to increase their production, such as the application of two-phase light cultivation systems, can stimulate pigments production, increasing economic turnover. In this sense, Cyanobium sp. was grown in seven different two-phase white/red cultivation arr...
Comparative outcome assessment of epidermal growth factor receptor tyrosine kin...
Mello, R; Escriu, C; Castelo-Branco, P; Cabral, P; Mountzios, G; Lopes, G; Madureira, PIntroduction: Tyrosine kinase inhibition of the epidermal growth factor receptor (EGFR) is the standard in the first line treatment of patients with advanced nonsmall- cell lung cancer (NSCLC) harbouring EGFR activating mutations. Here we aim to discern efficacy and toxicity measures through a meta-analysis of published studies that could aid treatment selection. Materials And Methods: We performed a meta-analy...
Osteomielite crónica multifocal recorrente: série de 4 casos clínicos tratados ...
Ferraria, N; Marques, JG; Ramos, F; Lopes, G; Fonseca, JG; Neves, MCAim: To report and describe a series of four cases of chronic recurrent multifocal osteomyelitis (CRMO) and to discuss therapeutic options, particularly bisphosphonate therapy. Methods: Retrospective review of four CRMO cases in two Pediatric Units in Lisbon, between 2005 and 2010. Results: Median age of first CRMO symptoms was 11.3 years (range 9-13). The more affected sites were the metaphysis of the long bon...
Kalirin: a novel genetic risk factor for ischemic stroke
Krug, T; Manso, H; Gouveia, L; Sobral, J; Xavier, J; Albergaria, I; Gaspar, G; Correia, M; Viana-Baptista, M; Simões, R; Pinto, A; Taipa, R; Ferreira, CCerebrovascular and cardiovascular diseases are the leading causes of death and disability worldwide. They are complex disorders resulting from the interplay of genetic and environmental factors, and may share several susceptibility genes. Several recent studies have implicated variants of the Kalirin (KALRN) gene with susceptibility to cardiovascular and metabolic phenotypes, but no studies have yet been perfo...
Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese pat...
Rosa, A; Fonseca, BV; Krug, T; Manso, H; Gouveia, L; Albergaria, I; Gaspar, G; Correia, M; Viana-Baptista, M; Simões, RM; Pinto, AN; Taipa, RBACKGROUND: The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to ...
Kalirin: a novel genetic risk factor for ischemic stroke
Krug, T; Manso, H; Gouveia, L; Sobral, J; Xavier, JM; Albergaria, I; Gaspar, G; Correia, M; Viana-Baptista, M; Simões, RN; Pinto, AN; Taipa, RCerebrovascular and cardiovascular diseases are the leading causes of death and disability worldwide. They are complex disorders resulting from the interplay of genetic and environmental factors, and may share several susceptibility genes. Several recent studies have implicated variants of the Kalirin (KALRN) gene with susceptibility to cardiovascular and metabolic phenotypes, but no studies have yet been perfo...
Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese pat...
Rosa, A; Fonseca, B; Krug, T; Manso, H; Gouveia, L; Albergaria, I; Gaspar, G; Correia, M; Viana-Baptista, M; Simões, R; Pinto, A; Taipa, R; Ferreira, CBACKGROUND: The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to ...
Slipped Capital Femoral Epiphysis. A Report of 4 Cases Occurring in One Family
Moreira, JF; Neves, MC; Lopes, G; Gomes, ARWe describe slipped capital femoral epiphysis in 4 members of a black, obese family, who were all first-degree relatives. The aetiology of slipped capital femoral epiphysis is unknown, although it is thought to be multifactorial. Genetic predisposition and environmental factors have been associated with the condition. A familial incidence with at least two cases in the same family has been reported. In epidemio...