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Reproductive factors, hormonal interventions, and gastric cancer risk in the St...

Song, M; Jayasekara, H; Pelucchi, C; Rabkin, CS; Johnson, KC; Hu, J; Palli, D; Ferraroni, M; Liao, LM; Bonzi, R; Zaridze, D; Maximovitch, D; Aragonés, N

Background: Gastric cancer incidence is higher in men, and a protective hormone-related effect in women is postulated. We aimed to investigate and quantify the relationship in the Stomach cancer Pooling (StoP) Project consortium. Methods: A total of 2,084 cases and 7,102 controls from 11 studies in seven countries were included. Summary odds ratios (ORs) and 95% confidence intervals (CIs) assessing associations...


Dietary intake of vitamin C and gastric cancer: a pooled analysis within the St...

Sassano, M; Seyyedsalehi, MS; Collatuzzo, G; Pelucchi, C; Bonzi, R; Ferraroni, M; Palli, D; Yu, G-P; Zhang, Z-F; López-Carrillo, L; Lunet, N; Morais, S

Background: Previous studies suggest that dietary vitamin C is inversely associated with gastric cancer (GC), but most of them did not consider intake of fruit and vegetables. Thus, we aimed to evaluate this association within the Stomach cancer Pooling (StoP) Project, a consortium of epidemiological studies on GC. Methods: Fourteen case–control studies were included in the analysis (5362 cases, 11,497 controls...


The Association between Peptic Ulcer Disease and Gastric Cancer: Results from t...

Paragomi, P; Dabo, B; Pelucchi, C; Bonzi, R; Bako, AT; Sanusi, NM; Nguyen, QH; Zhang, Z-F; Palli, D; Ferraroni, M; Vu, KT; Yu, G-P; Turati, F

Background. Gastric cancer (GC) is the fifth most common type of cancer and the fourth most common cause of cancer-related mortality. Although the risk of GC and peptic ulcer disease (PUD) is known to be increased by H. pylori infection, evidence regarding the direct relationship between PUD and GC across ethnicities is inconclusive. Therefore, we investigated the association between PUD and GC in the Stomach c...


Salt intake and gastric cancer: a pooled analysis within the Stomach cancer Poo...

Morais, S; Costa, A; Albuquerque, G; Araújo, N; Pelucchi, C; Rabkin, CS; Liao, LM; Sinha, R; Zhang, Z-F; Hu, J; Johnson, KC; Palli, D; Ferraroni, M

Purpose: Previous studies show that consuming foods preserved by salting increases the risk of gastric cancer, while results on the association between total salt or added salt and gastric cancer are less consistent and vary with the exposure considered. This study aimed to quantify the association between dietary salt exposure and gastric cancer, using an individual participant data meta-analysis of studies pa...


The association between diabetes and gastric cancer: results from the Stomach C...

Dabo, B; Pelucchi, C; Rota, M; Jain, H; Bertuccio, P; Bonzi, R; Palli, D; Ferraroni, M; Zhang, Z-F; Sanchez-Anguiano, A; Thi-Hai, Pham, Y

Background Prior epidemiologic studies on the association between diabetes and gastric cancer risk provided inconclusive findings, while traditional, aggregate data meta-analyses were characterized by high between-study heterogeneity. Objective To investigate the association between type 2 diabetes and gastric cancer using data from the 'Stomach Cancer Pooling (StoP) Project', an international consortium of mor...


Inverse Association between Dietary Iron Intake and Gastric Cancer: A Pooled An...

Collatuzzo, G; Teglia, F; Pelucchi, C; Negri, E; Rabkin, CS; Liao, LM; Sinha, R; López‐carrillo, L; Lunet, N; Morais, S; Aragonés, N; Moreno, V

Background: Inconsistent findings have been reported regarding the relationship between dietary iron intake and the risk of gastric cancer (GC). Methods: We pooled data from 11 case‐control studies from the Stomach Cancer Pooling (StoP) Project. Total dietary iron intake was derived from food frequency questionnaires combined with national nutritional tables. We derived the odds ratios (ORs) and 95% confidence ...


Coffee consumption and gastric cancer: A pooled analysis from the Stomach cance...

Martimianaki, G; Bertuccio, P; Alicandro, G; Pelucchi, C; Bravi, F; Carioli, G; Bonzi, R; Rabkin, CS; Liao, LM; Sinha, R; Johnson, K; Hu, J; Palli, D

Objective This study aimed to evaluate and quantify the relationship between coffee and gastric cancer using a uniquely large dataset from an international consortium of observational studies on gastric cancer, including data from 18 studies, for a total of 8198 cases and 21 419 controls. Methods A two-stage approach was used to obtain the pooled odds ratios (ORs) and the corresponding 95% confidence intervals ...


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