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The association between dietary fiber intake and gastric cancer: a pooled analy...

Collatuzzo, G; Cortez Lainez, J; Pelucchi, C; Negri, E; Bonzi, R; Palli, D; Ferraroni, M; Zhang, ZF; Yu, GP; Lunet, N; Morais, S; López-Carrillo, L

"Purpose: Gastric cancer (GC) is among the leading causes of cancer mortality worldwide. The objective of this study was to investigate the association between dietary fiber intake and GC. Methods: We pooled data from 11 population or hospital-based case-control studies included in the Stomach Cancer Pooling (StoP) Project, for a total of 4865 histologically confirmed cases and 10,626 controls. Intake of dietar...


The global gastric cancer consortium: an update from the Stomach cancer Pooling...

Pelucchi, C; La Vecchia, C; Bonzi, R; Negri, E; Corso, G; Boccia, S; Boffetta, P; Camargo, MC; Curado, MP; Lunet, N; Vioque, J; Zhang, ZF

We updated to December 2023 the main findings of the stomach cancer pooling (StoP) project including about 13 000 cases and 31 000 controls from 29 case–control and 5 nested studies. The StoP project quantified more precisely than previously available the positive associations of tobacco smoking, high alcohol consumption, meat intake, selected occupations (e.g. agricultural and miners), gastric ulcer and family...


The protective effect of dietary folate intake on gastric cancer is modified by...

Gonzalez-Palacios, S; Compañ-Gabucio, LM; Torres-Collado, L; Oncina-Canovas, A; García-de-la-Hera, M; Collatuzzo, G; Negri, E; Pelucchi, C; Rota, M

Dietary folate intake has been identified as a potentially modifiable factor of gastric cancer (GC) risk, although the evidence is still inconsistent. We evaluate the association between dietary folate intake and the risk of GC as well as the potential modification effect of alcohol consumption. We pooled data for 2829 histologically confirmed GC cases and 8141 controls from 11 case–control studies from the int...


Global age-sex-specific mortality, life expectancy, and population estimates in...

Schumacher, AE; Kyu, HH; Aali, A; Abbafati, C; Abbas, J; Abbasgholizadeh, R; Abbasi, MA; Abbasian, M; Abd ElHafeez, S; Abdelmasseh, M; Abd Elsalam, S

Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides n...


Mushroom consumption and risk of gastric cancer: a pooled analysis within the s...

Ba, DM; Ssentongo, P; Pelucchi, C; Negri, E; Palli, D; Ferraroni, M; Zhang, ZF; Yu, GP; Tsugane, S; Hidaka, A; Hamada, GS; Zaridze, D; Maximovich, D

Edible mushrooms have high concentrations of vitamins and minerals. They are considered ‘functional foods’ for their disease-prevention properties. Mushroom consumption may reduce the risk of gastric cancer, the fifth most common cancer worldwide. We investigated the association between mushroom consumption and gastric cancer risk in a pooled analysis within the Stomach Cancer Pooling (StoP) Project and in a me...


Yoghurt Intake and Gastric Cancer: A Pooled Analysis of 16 Studies of the StoP ...

Collatuzzo, G; Negri, E; Pelucchi, C; Bonzi, R; Turati, F; Rabkin, CS; Liao, LM; Sinha, R; Palli, D; Ferraroni, M; López-Carrillo, L; Lunet, N

Background: Yoghurt can modify gastrointestinal disease risk, possibly acting on gut microbiota. Our study aimed at exploring the under-investigated association between yoghurt and gastric cancer (GC). Methods: We pooled data from 16 studies from the Stomach Cancer Pooling (StoP) Project. Total yoghurt intake was derived from food frequency questionnaires. We calculated study-specific odds ratios (ORs) of GC an...


Sleep Duration and Stress Level in the Risk of Gastric Cancer: A Pooled Analysi...

Collatuzzo, G; Pelucchi, C; Negri, E; Kogevinas, M; Huerta, JM; Vioque, J; de la Hera, MG; Tsugane, S; Hamada, GS; Hidaka, A; Zhang, ZF; Camargo, MC

The association between sleep and stress and cancer is underinvestigated. We evaluated these factors in association with gastric cancer (GC). Five case-control studies from the Stomach Cancer Pooling (StoP) Project were included. We calculated the odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) for sleep duration and stress level in association with GC through multiple logistic regression...


The mediating role of combined lifestyle factors on the relationship between ed...

Alicandro, G; Bertuccio, P; Collatuzzo, G; Pelucchi, C; Bonzi, R; Liao, LM; Rabkin, CS; Sinha, R; Negri, E; Dalmartello, M; Zaridze, D; Maximovich, D

Background: The causal pathway between high education and reduced risk of gastric cancer (GC) has not been explained. The study aimed at evaluating the mediating role of lifestyle factors on the relationship between education and GC Methods: Ten studies with complete data on education and five lifestyle factors (smoking, alcohol drinking, fruit and vegetable intake, processed meat intake and salt consumption) w...


Identifying the Profile of Helicobacter pylori-Negative Gastric Cancers: A Case...

Morais, S; Peleteiro, B; Araújo, N; Malekzadeh, R; Ye, W; Plymoth, A; Tsugane, S; Hidaka, A; Hamada, GS; López-Carrillo, L; Zaridze, D; Maximovich, D

Background: The prevalence of Helicobacter pylori-negative gastric cancer (HpNGC) can be as low as 1%, when infection is assessed using more sensitive tests or considering the presence of gastric atrophy. HpNGC may share a high-risk profile contributing to the occurrence of cancer in the absence of infection. We estimated the proportion of HpNGC, using different criteria to define infection status, and compared...


Family History and Gastric Cancer Risk: A Pooled Investigation in the Stomach C...

Vitelli-Storelli, F; Rubín-García, M; Pelucchi, C; Benavente, Y; Bonzi, R; Rota, M; Palli, D; Ferraroni, M; Lunet, N; Morais, S; Ye, W; Plymoth, A

Although there is a clear relationship between family history (FH) and the risk of gastric cancer (GC), quantification is still needed in relation to different histological types and anatomical sites, and in strata of covariates. The objective was to analyze the risk of GC according to first-degree FH in a uniquely large epidemiological consortium of GC. This investigation includes 5946 cases and 12,776 control...


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