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Conotoxin loaded dextran microgel particles alleviate effects of spinal cord in...
Zhao, X.; Jin, L.; Zhu, Z.; Lu, H.; Shi, H.; Zhong, Q.; Oliveira, J. M.; Reis, R. L.; Gao, C.; Zhengwei, M.Spinal cord injury (SCI) is a severe refractory disabling condition accompanied by complicated patholog- ical processes, such as excessive glutamate release in the extracellular environment and massive influx of Ca 2 + into cells. Dextran can absorb extracellular glutamate and Ca 2 + to attenuate persistent excita- tory processes that are detrimental to normal cells. Calcium channel inhibitors reduce the influx...
Date: 2021
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Origin: RepositóriUM - Universidade do Minho