13 documents found, page 1 of 2
The carotid body detects circulating tumor necrosis factor-alpha to activate a ...
Katayama, Pedro L. [UNESP]; Leirão, Isabela P. [UNESP]; Kanashiro, Alexandre; Luiz, João P.M.; Cunha, Fernando Q.; Navegantes, Luiz C.C.Made available in DSpace on 2022-04-29T08:46:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-05-01; Booz Allen Foundation; Recent evidence has suggested that the carotid bodies might act as immunological sensors, detecting pro-inflammatory mediators and signalling to the central nervous system, which, in turn, orchestrates autonomic responses. Here, we confirmed that the TNF-α receptor type I is expre...
Acute intermittent hypoxia evokes ventilatory long-term facilitation and active...
Mendonça-Junior, Bolival A. [UNESP]; V. Fernandes, Marcos [UNESP]; Zoccal, Daniel B. [UNESP]Made available in DSpace on 2022-04-29T08:31:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Acute intermittent hypoxia (AIH) modifies the functioning of the respiratory network, causing respirat...
Lesion of Serotonergic Afferents to the Retrotrapezoid Nucleus Impairs the Tach...
Leirão, Isabela P. [UNESP]; Colombari, Débora S.A. [UNESP]; da Silva, Glauber S.F.; Zoccal, Daniel B. [UNESP]Made available in DSpace on 2021-06-25T10:17:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Hypercapnia promotes an increase in pulmonary ventilation due to the stimulation of brainstem chemosensory cells that are connected to the respiratory network. Among these...
Differential modulation of active expiration during hypercapnia by the medullar...
Leirão, Isabela P. [UNESP]; Zoccal, Daniel B. [UNESP]; Gargaglioni, Luciane H. [UNESP]; da Silva, Glauber S. F.Made available in DSpace on 2021-06-25T10:33:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01; Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Pró-Reitoria de Pesquisa, Universidade Federal de Minas Gerais; Active expiration represents an important mechanism to improve ventilation in conditions of augmented ventilat...
Leptin: Master regulator of biological functions that affects breathing
Gauda, Estelle B.; Conde, Silvia; Bassi, Mirian [UNESP]; Zoccal, Daniel B. [UNESP]; Colombari, Debora Simoes Almeida [UNESP]; Colombari, Eduardo [UNESP]Made available in DSpace on 2020-12-12T02:49:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Obesity is a global epidemic in developed countries accounting for many of the metabolic and cardiorespiratory morbidities that occur in adults. These morbidities include type 2 diabetes, sleepdisordered breathing (SDB), obstructive sleep apnea, chronic intermittent hypoxia, and hypertension. Leptin, pr...
Serotonin and the control of eupneic breathing
Zoccal, Daniel B. [UNESP]Made available in DSpace on 2020-12-12T01:16:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-01-01; The mechanisms responsible for respiratory rhythm and pattern generation are continuously tuned by neuromodulators. Serotonin is a powerful modulator of the respiratory network that regulates synaptic and intrinsic properties of respiratory neurons that, in turn, may differentially affect the frequency ...
Inhibitory control of active expiration by the Bötzinger complex in rats
Flor, Karine C. [UNESP]; Barnett, William H.; Karlen-Amarante, Marlusa [UNESP]; Molkov, Yaroslav I.; Zoccal, Daniel B. [UNESP]Made available in DSpace on 2020-12-12T02:16:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Key points: Contraction of abdominal muscles at the end of expiration during metabolic challenges (such as hypercapnia and hypoxia) improves pulmonary ventilation. The emergence of this active expiratory pattern requires the recruitment of the expiratory oscillator located on the ventral surface of the ...
Modulation of hypercapnic respiratory response by cholinergic transmission in t...
Furuya, Werner I. [UNESP]; Bassi, Mirian [UNESP]; Menani, José V. [UNESP]; Colombari, Eduardo [UNESP]; Zoccal, Daniel B. [UNESP]Made available in DSpace on 2020-12-12T02:32:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); The nucleus of the solitary tract (NTS) is an important area of the brainstem that receives and integr...
Renovascular hypertension elevates pulmonary ventilation in rats by carotid bod...
Melo, Mariana Rosso [UNESP]; Gasparini, Silvia [UNESP]; Silva, Elaine F. [UNESP]; Karlen-Amarante, Marlusa [UNESP]; Speretta, Guilherme F. [UNESP]Made available in DSpace on 2020-12-12T02:38:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-02-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The two kidney-one clip (2K1C) renovascular hypertension depends on the renin-angiotensin system and sympathetic overactivity. The maintenance of 2K1C hypertension also de...
Postnatal intermittent hypoxia enhances phrenic and reduces vagal upper airway ...
Bittencourt-Silva, Paloma G. [UNESP]; Menezes, Miguel Furtado [UNESP]; Mendonça-Junior, Bolival A. [UNESP]; Karlen-Amarante, Marlusa [UNESP]Made available in DSpace on 2020-12-12T01:46:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); New Findings: What is the central question of this study? What are the alterations in respiratory motor activity that may underlie ventilatory dysfunctions in juvenile and adult animals exposed to postnatal chronic intermittent hypoxi...