4 documents found, page 1 of 1
Attachment and proliferation of osteoblasts on lithium-hydroxyapatite composites
Schainberg, Ana Paula Muchon; Valério, Patrícia; Zonari, Alessandra; Oktar, Faik Nushek; Ozyegin, Luftie Sevgi; Graça, Manuel Pedro FernandesThe biocompatibility and bioactivity properties of hydroxyapatites (HAs) modified through lithium addition were investigated. Hydroxyapatites obtained from bovine bone were mixed with lithium carbonate (Li), in the proportions of 0.25, 0.50, 1.00, and 2.00%wt, and sintered at 900◦, 1000◦, 1100◦, 1200◦, and 1300◦C, creating LiHA samples. The osteoblast culture behavior was assessed in the presence of these LiHA ...
The Kinetics of Small Extracellular Vesicle Delivery Impacts Tissue Regeneration
Antunes, Helena; Cardoso, Renato; Zonari, Alessandra; Correia, Joana; Leal, Ermelindo; Jiménez-Balsa, Adrián; Lino, Miguel; Barradas, Ana; Kostic, IvanaFCT (SFRH/BDE/103512/2014;SFRH/BPD/112883/2015; SFRH/BPD/97286/2013; MITP-TB/ECE/0013/2013; EXCL/DTP-PIC/0069/2012; UID/NEU/04539/2013); EFSD/JDRF/Novo Nordisk European Programme in Type 1 Diabetes Research; QREN-COMPETE funding (FCOMP-01-0202-FEDER-038631; Project “ExoCord” promoted by Stemlab, SA and Biocant), Portugal 2020-COMPETE funding (Project “Stem cell based platforms for Regenerative and Therapeutic M...
Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers
Lino, Miguel M.; Simões, Susana; Vilaça, Andreia; Antunes, Helena; Zonari, Alessandra; Ferreira, Lino"This document is the unedited Author's version of a Submitted Work that was subsequently accepted for publication in [JournalTitle], copyright © American Chemical Society after peer review. To access the final edited and published work see [insert ACS Articles on Request author-directed link to Published Work, see https://pubs.acs.org/doi/ipdf/10.1021/acsnano.7b07538; The authors are grateful for the financial...
Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin reg...
Comune, Michela; Rai, Akhilesh; Chereddy, Kiran K; Pinto, Sandra; Aday, Sezin; Ferreira, André F; Zonari, Alessandra; Blersch, JosephineChronic skin wounds affect ≈3% of persons aged >60years (Davies et al., 2007) [1]. These wounds are typically difficult to heal by conventional therapies and in many cases they get infected making even harder the regeneration process. The antimicrobial peptide (AMP) LL37 combines antimicrobial with pro-regenerative properties and thus represents a promising topical therapy to address both problems. Here, we inv...