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Neuregulin-1 improves right ventricular function and attenuates experimental pu...

Mendes-Ferreira, P.; Maia-Rocha, C.; Adão, R.; Mendes, M.J.; Santos-Ribeiro, D.; Silvana Alves, B.; Cerqueira, R.J.; Castro-Chaves, P.; Lourenço, A.P.

Aims Pulmonary arterial hypertension (PAH) is a serious disease that affects both the pulmonary vasculature and the right ventricle (RV). Current treatment options are insufficient. The cardiac neuregulin (NRG)-1/ErbB system is deregulatedduring heart failure, and treatment with recombinant human NRG-1 (rhNRG-1) has been shown to be beneficial inanimal models and in patients with left ventricular (LV) dysfuncti...


NRG-1 improves right ventricular function in pulmonary hypertension

Mendes-Ferreira, P.; Maia-Rocha, C.; Adão, R.; Lourenço, A.P.; Moura, C.; Pinho, S.; Areias, J.C.; De keulenaer, G.W.; Leite-Moreira, A.F.

[abstract]


A neuregulina atenua a hipertrofia e a disfunção ventricular direitas num model...

Mendes-Ferreira, P.; Maia-Rocha, C.; Adão, R.; Lourenço, A.P.; Moura, C.; Mendes,M.J.; Pinho, S.; Areias, J.C.; De Keulenaer, G.W.; Leite-Moreira, A.F.

[abstract]


Neuregulin Attenuates Right Ventricular and Pulmonary Endothelial Dysfunction i...

Mendes-Ferreira, P.; Maia-Rocha, C.; Adão, R.; Cerqueira, R.; Mendes, M.J.; Lourenço, A.P.; Keulenaer, G.; Leite-Moreira, A.; Brás-Silva, C.

[abstract]


Neuregulin attenuates right ventricular hypertrophy and dysfunction in an exper...

Maia-Rocha, C.; Adão, R.; Mendes-Ferreira, P.; Mendes, M.J.; Pinho, S.; Lourenço, A.P.; De Keulenaer, G.W.; Leite-Moreira, A.F.; Brás-Silva, Carmen

[abstract]


Neuregulin attenuates right ventricular hypertrophy and dysfunction in an exper...

Mendes-Ferreira, P.; Maia-Rocha, C.; Adão, R.; Lourenço, A.P.; Cerqueira, R.; Mendes, M.J.; Castro-Chaves, P.; De Keulenaer, G.W.; Leite-Moreira, A.F.

[abstract]


Acute haemodynamic effects of tezosentan in rats with monocrotaline-induced pul...

Lourenço, A.P.; Viterbo, J.F.; Brás-Silva C; Vieira, F.; Moreira, Adelino Leite

[abstract]


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