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The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity...
Gouveia, Maria João; Brindley, Paul J.; Azevedo, Carlos; Gärtner, Fátima; da Costa, José M. C.; Vale, NunoBackground: Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel (PZQ) for more than a generation. Despite its celebrated performance for treatment and control of schistosomiasis and other platyhelminth infections, praziquantel has some shortcomings and the inability of this drug to counteract disease sequelae prompts the need for novel therapeutic strategies. Methods: Using a host-para...
Data: 2019
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Origem: Repositório Científico do Instituto Nacional de Saúde