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Persistence of mcr-1-carrying E. coli in rabbit meat production: Challenges bey...

Ribeiro-Almeida, M; Mourao, J; Rodrigues, IC; de Carvalho, AP; da Costa, PM; Peixe, L; Antunes, Patrícia

Colistin, a last-resort antibiotic in human medicine, has been banned in European food animal production to mitigate antimicrobial resistance. This study investigates the long-term effects of the colistin ban on the occurrence and genomic features (WGS) of colistin-resistant, mcr-carrying Escherichia coli across intensive rabbit farms (8 farms, similar to 600 animals/farm, fecal and farm environmental samples) ...


Root causes and outcomes of postoperative pulmonary complications after abdomin...

Fernandes, A; Rodrigues, J; Lages, P; Lanca, S; Mendes, P; Antunes, L; Santos, CS; Castro, C; Costa, RS; Lopes, CS; da Costa, PM; Santos, LL

Background: Postoperative pulmonary complications (PPCs) contribute significantly to overall postoperative morbidity and mortality. In abdominal surgery, PPCs remain frequent. The study aimed to analyze the profile and outcomes of PPCs in patients submitted to abdominal surgery and admitted in a Portuguese polyvalent intensive care unit. Methods: From January to December 2017 in the polyvalent intensive care un...


Occurrence of mcr-1 in Escherichia coli from rabbits of intensive farming

Freitas Silva, J; Inácio, ÂS; Mourão, J.; Antunes, Patrícia; Mendes, Â; de Carvalho, AP; Vasconcelos, V; Peixe, L.; da Costa, PM

The emergence of mobile colistin resistance genes (mcr) is yet another challenge in the fight against antimicrobial resistance, with reports proving the dissemination of these genes in different countries and different environments being of great concern. In the present study, we describe the recovery of three E. coli strains with mcr-1 gene in IncHI2 plasmids from intestinal content of necropsied meat rabbits ...


Prevalence of antimicrobial resistance in enteric Escherichia coli from domesti...

Leite-Martins, LR; Mahú, MI; Costa, AL; Mendes, A; Lopes, E; Mendonça, DM; Niza-Ribeiro, JJ; de Matos, AJ; da Costa, PM

Antimicrobial resistance (AMR) is a growing global public health problem, which is caused by the use of antimicrobials in both human and animal medical practice. The objectives of the present cross-sectional study were as follows: (1) to determine the prevalence of resistance in Escherichia coli isolated from the feces of pets from the Porto region of Portugal against 19 antimicrobial agents and (2) to assess t...


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