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Criterion and construct validity of the Beck Depression Inventory (BDI-II) to m...

Almeida, Sílvia; Camacho, Marta; Barahona-Corrêa, J. Bernardo; Oliveira, José; Lemos, Raquel; Da Silva Rodrigues, Daniel; da Silva, Joaquim Alves

Background/Objective: Screening for depression in patients with cancer can be difficult due to overlap between symptoms of depression and cancer. We assessed validity of the Beck Depression Inventory (BDI-II) in this population. Method: Data was obtained in an outpatient neuropsychiatry unit treating patients with and without cancer. Psychometric properties of the BDI-II Portuguese version were assessed separat...


Neuro-mesenchymal units control ILC2 and obesity via a brain–adipose circuit

Cardoso, Ana; Klein Wolterink, Roel G. J.; Godinho-Silva, Cristina; Domingues, Rita G.; Ribeiro, Hélder; da Silva, Joaquim Alves; Mahú, Inês

Signals from sympathetic neurons and immune cells regulate adipocytes and thereby contribute to fat tissue biology. Interactions between the nervous and immune systems have recently emerged as important regulators of host defence and inflammation1-4. Nevertheless, it is unclear whether neuronal and immune cells co-operate in brain-body axes to orchestrate metabolism and obesity. Here we describe a neuro-mesench...


Light-entrained and brain-tuned circadian circuits regulate ILC3s and gut homeo...

Godinho-Silva, Cristina; Domingues, Rita G.; Rendas, Miguel; Raposo, Bruno; Ribeiro, Hélder; da Silva, Joaquim Alves; Vieira, Ana I. S.; Costa, Rui M

Group 3 innate lymphoid cells (ILC3s) are major regulators of inflammation, infection, microbiota composition and metabolism1. ILC3s and neuronal cells have been shown to interact at discrete mucosal locations to steer mucosal defence2,3. Nevertheless, it is unclear whether neuroimmune circuits operate at an organismal level, integrating extrinsic environmental signals to orchestrate ILC3 responses. Here we sho...


Club drugs.

Guerreiro, Diogo Frasquilho; Carmo, Ana Lisa; da Silva, Joaquim Alves; Navarro, Rita; Góis, Carlos

Club drugs are the following substances: Methylenedioxymethamphetamine (MDMA); Methamphetamine; Lysergic Acid Diethylamide (LSD); Ketamine; Gamma-hydroxybutyrate (GHB) and Flunitrazepam. These substances are mainly used by adolescents and young adults, mostly in recreational settings like dance clubs and rave parties. These drugs have diverse psychotropic effects, are associated with several degrees of toxicity...

Date: 2011   |   Origin: Acta Médica Portuguesa

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