7 documents found, page 1 of 1
LncRNA HOTAIR is a novel endothelial mechanosensitive gene
da Silva, Rodrigo A. [UNESP]; Ferreira, Marcel Rodrigues [UNESP]; Gomes, Anderson Moreira [UNESP]; Zambuzzi, Willian F. [UNESP]Made available in DSpace on 2020-12-12T01:44:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); To better address whether the long noncoding RNAs (lncRNAs) HOTAIR and HOTTIP are mechanosensitive genes, they were investigated in differentially challenged endothelial c...
Osteogenic gene markers are epigenetically reprogrammed during contractile-to-c...
da Silva, Rodrigo A. [UNESP]; da S. Feltran, Geórgia [UNESP]; da C. Fernandes, Célio Júnior [UNESP]; Zambuzzi, Willian F. [UNESP]Made available in DSpace on 2020-12-12T01:48:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-02-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The understanding of vascular calcification-based mechanism is an urgent pending task in vascular biology and this prompted us to better address this issue by investigating whether DNA methylation mechanism might drive osteogenic mark...
Wortmannin targeting phosphatidylinositol 3-kinase suppresses angiogenic factor...
Gomes, Anderson M. [UNESP]; Pinto, Thais S. [UNESP]; da Costa Fernandes, Célio J. [UNESP]; da Silva, Rodrigo A. [UNESP]; Zambuzzi, Willian F. [UNESP]Made available in DSpace on 2020-12-12T01:08:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-06-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Modifications on shear stress-based mechanical forces are associated with pathophysiological susceptibility and their effect on endothelial cells (EC) needs to be better a...
The role of triiodothyronine hormone and mechanically-stressed endothelial cell...
da Silva, Rodrigo A. [UNESP]; de Camargo Andrade, Amanda Fantini [UNESP]; da Silva Feltran, Geórgia [UNESP]; Fernandes, Célio Júnior da C. [UNESP]Made available in DSpace on 2019-10-06T15:57:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-15; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); We therefore investigated whether there is synergism between triiodothyronine (T3) hormone and trophic molecules released from mechanically-stressed endothelial cells (EC-...
HOXA cluster gene expression during osteoblast differentiation involves epigene...
da Silva, Rodrigo A. [UNESP]; Fuhler, Gwenny M.; Janmaat, Vincent T.; da C. Fernandes, Célio Júnior [UNESP]; da Silva Feltran, Geórgia [UNESP]Made available in DSpace on 2019-10-06T16:30:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The HOXA gene cluster is generally recognized as a pivotal mediator of positional identity in the skeletal system, expression of different orthologues conferring alternati...
Phosphoproteome analysis reveals a critical role for hedgehog signalling in ost...
Marumoto, Ariane [UNESP]; Milani, Renato; da Silva, Rodrigo A. [UNESP]; da Costa Fernandes, Célio Junior [UNESP]; Granjeiro, José MauroMade available in DSpace on 2018-12-11T17:12:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The reciprocal and adaptive interactions between cells and substrates governing morphological transitions in the osteoblast compartment remain largely obscure. Here we sho...
Fibroblast contributes for osteoblastic phenotype in a MAPK-ERK and sonic hedge...
da Costa Fernandes, Celio J. [UNESP]; do Nascimento, Augusto Santana [UNESP]; da Silva, Rodrigo A. [UNESP]; Zambuzzi, Willian F. [UNESP]Made available in DSpace on 2018-12-11T16:47:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); We hypothesized that a crosstalk between osteoblast and fibroblast (FB) exists, which contributes to bone as a dynamic tissue. Cell-free supernatants were harvested from f...