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Global excess deaths associated with heatwaves in 2023 and the contribution of ...

Hundessa, Samuel; Huang, Wenzhong; Xu, Rongbin; Yang, Zhengyu; Zhao, Qi; Gasparrini, Antonio; Armstrong, Ben; Bell, Michelle L.; Huber, Veronika

Abstract: An unprecedented heatwave swept the globe in 2023, marking it one of the hottest years on record and raising concerns about its health impacts. However, a comprehensive assessment of the heatwave-related mortality and its attribution to human-induced climate change remains lacking. We aim to address this gap by analyzing high-resolution climate and mortality data from 2,013 locations across 67 countri...


The effectiveness of heat prevention plans in reducing heat-related mortality a...

Urban, Aleš; Huber, Veronika; Henry, Salomé; Plaza, Nuria Pilar; Tušlová, Lucie; Dasgupta, Shouro; Masselot, Pierre; Cvijanovic, Ivana; Mistry, Malcolm

Heat-health warning systems and action plans, referred to as heat prevention plans (HPPs), are key public health interventions aimed at reducing heat-related mortality. Despite their importance, prior assessments of their effectiveness have yielded inconsistent results. The objective of this study is to systematically assess the effectiveness of HPPs in reducing heat-related mortality risk across Europe. We ana...


Short-term association between hot nights and mortality: a multicountry analysi...

Royé, Dominic; Sera, Francesco; Tobías, Aurelio; Hashizume, Masahiro; Honda, Yasushi; Kim, Ho; Vicedo-Cabrera, Ana Maria; Tong, Shilu; Lavigne, Eric

Background: The rise in hot nights over recent decades and projections of further increases due to climate change underscores the critical need to understand their impact. This knowledge is essential for shaping public health strategies and guiding adaptation efforts. Despite their significance, research on the implications of hot nights remains limited. Objective: This study estimated the association between h...


Estimating the urban heat-related mortality burden due to greenness: a global m...

Wu, Yao; Wen, Bo; Ye, Tingting; Huang, Wenzhong; Liu, Yanming; Gasparrini, Antonio; Sera, Francesco; Tong, Shilu; Lavigne, Eric; Roye, Dominic

Background: Heat exposure poses a substantial public health threat. Increasing greenness has been suggested as a mitigation strategy due to its cooling effect and potential to modify the heat-mortality association. This study aimed to comprehensively estimate the effects of increased greenness on heat-related deaths. Methods: We applied a multistage meta-analytical approach to estimate the potential reduction i...


Temporal change in minimum mortality temperature under changing climate: A mult...

Yang, Daewon; Hashizume, Masahiro; Tobías, Aurelio; Honda, Yasushi; Roye, Dominic; Oh, Jaemin; Dang, Tran Ngoc; Kim, Yoonhee; Abrutzky, Rosana

Background: The minimum mortality temperature (MMT) or MMT percentile (MMTP) is an indicator of population susceptibility to nonoptimum temperatures. MMT and MMTP change over time; however, the changing directions show region-wide heterogeneity. We examined the heterogeneity of temporal changes in MMT and MMTP across multiple communities and in multiple countries. Methods: Daily time-series data for mortality a...


Temperature frequency and mortality: Assessing adaptation to local temperature

Wu, Yao; Wen, Bo; Gasparrini, Antonio; Armstrong, Ben; Sera, Francesco; Lavigne, Eric; Li, Shanshan; Guo, Yuming; Overcenco, Ala; Urban, Aleš

Assessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on mortality and temperature from 757 locations in 47 countries/regions during 1979–2020. We used a two-stage time series design to assess the association between temperature frequency and all-cause mortality. The results were pooled ...


Temporal variations in the short-term effects of ambient air pollution on cardi...

Schwarz, Maximilian; Peters, Annette; Stafoggia, Massimo; de'Donato, Francesca; Sera, Francesco; Bell, Michelle L; Guo, Yuming; Honda, Yasushi

Background: Ambient air pollution, including particulate matter (such as PM10 and PM2·5) and nitrogen dioxide (NO2), has been linked to increases in mortality. Whether populations' vulnerability to these pollutants has changed over time is unclear, and studies on this topic do not include multicountry analysis. We evaluated whether changes in exposure to air pollutants were associated with changes in mortality ...


All-cause, cardiovascular, and respiratory mortality and wildfire-related ozone...

Chen, Gongbo; Guo, Yuming; Yue, Xu; Xu, Rongbin; Yu,Wenhua; Ye, Tingting; Tong, Shilu; Gasparrini, Antonio; Bell,Michelle L.; Armstrong, Ben

Background: Wildfire activity is an important source of tropospheric ozone (O3) pollution. However, no study to date has systematically examined the associations of wildfire-related O3 exposure with mortality globally. Methods: We did a multicountry two-stage time series analysis. From the Multi-City Multi-Country (MCC) Collaborative Research Network, data on daily all-cause, cardiovascular, and respiratory dea...


Global, regional, and national burden of mortality associated with cold spells ...

Gao, Yuan; Huang, Wenzhong; Zhao, Qi; Ryti, Niilo; Armstrong, Ben; Gasparrini, Antonio; Tong, Shilu; Pascal, Mathilde; Urban, Aleš; Zeka, Ariana

Background: Exposure to cold spells is associated with mortality. However, little is known about the global mortality burden of cold spells. Methods: A three-stage meta-analytical method was used to estimate the global mortality burden associated with cold spells by means of a time series dataset of 1960 locations across 59 countries (or regions). First, we fitted the location-specific, cold spell-related morta...


Heat-related cardiorespiratory mortality: Effect modification by air pollution ...

Rai, Masna; Stafoggia, Massimo; de'Donato, Francesca; Scortichini, Matteo; Zafeiratou, Sofia; Vazquez Fernandez, Liliana; Zhang, Siqi; Katsouyanni, Klea

Highlights: - Heat effect modification by air pollution on cardiovascular and respiratory mortality was investigated across 482 cities.- Heat effect was seen to be significantly modified by air pollutants PM10, PM2.5, O3, and NO2. -This study is the most extensive research to date investigating the heat effect modification on cardiovascular and respiratory mortality. - This is the first-ever study to deeply inv...


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