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Innate immune evasion revealed in a colorectal zebrafish xenograft model

Póvoa, Vanda; Rebelo de Almeida, Cátia; Maia-Gil, Mariana; Sobral, Daniel; Domingues, Micaela; Martinez-Lopez, Mayra; de Almeida Fuzeta, Miguel

LISBOA-01-0145-FEDER-022170 CEECIND/ 02699/2017; Cancer immunoediting is a dynamic process of crosstalk between tumor cells and the immune system. Herein, we explore the fast zebrafish xenograft model to investigate the innate immune contribution to this process. Using multiple breast and colorectal cancer cell lines and zAvatars, we find that some are cleared (regressors) while others engraft (progressors) in ...


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