Made available in DSpace on 2020-12-12T01:11:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Background APPL1, an adapter protein, interact directly with adiponectin receptors mediating adiponectin signaling and acting as a critical regulator of the crosstalk between adiponectin and insulin signaling pathway. The inadequate level of physical activity, high-calorie intake, or both lead to advers...
Made available in DSpace on 2018-12-11T16:50:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-10-09; Mitogen-activated Protein Kinase Phosphatase 3 (MKP-3) has been involved in the negative regulation of insulin signaling. The absence of MKP-3 is also associated with reduced adiposity, increased energy expenditure and improved insulin sensitivity. The MKP-3 is known as the main Erk1/2 phosphatase and F...