Made available in DSpace on 2022-04-29T08:45:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-02; Candida albicans is the main fungal species associated with the development of oral candidiasis. Currently, therapeutic options for these infections are limited by the adverse effects of antifungal drugs and by the emergence of drug resistant strains. Thus, the development of new antifungal agents is ne...
Made available in DSpace on 2022-04-29T08:41:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-04-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Background: Cancer is currently a major public health problem worldwide, with a marked increase of about 70% in the number of expected diagnosed cases over the next two decades. The amount of tobacco and alcohol consumed is calculated based ...
Made available in DSpace on 2022-05-01T11:54:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Natural latex serum (NLS) is one of the natural rubber latex fractions from Hevea brasiliensis tree, which is formed by centrifuged serum and is composed of proteins, acids, nucleotides, salts and carbohydrates. The proteins present in NLS have demonstrated several interesting biological properties, inc...
Made available in DSpace on 2021-06-25T11:04:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Streptococcus mutans is considered to be a major bacterium involved in dental caries, and the control of virulence mechanisms is fundamental to prevent disease. Probiotics...
Made available in DSpace on 2021-06-25T11:05:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Chitosan (CS), a biopolymer with intrinsic antimicrobial activity, can increase antimicrobial photodynamic inactivation (aPDI). The aim of this study was to evaluate the capacity of CS to potentiate the efficacy of Photoditazine® (PDZ)...
Made available in DSpace on 2021-06-25T11:15:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01; Photodynamic therapy (PDT) is a promising strategy to control cariogenic pathogens, such as Streptococcus mutans. Seeking to reach the total bacterial elimination from dental surfaces, novel photosensitizers have been investigated, such as Fotoenticine (FTC) derived from chlorin e6. The objective of thi...
Made available in DSpace on 2020-12-12T02:42:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-06-01; National Institutes of Health; Probiotics might provide an alternative approach for the control of oral candidiasis. However, studies on the antifungal activity of probiotics in the oral cavity are based on the consumption of yogurt or other dietary products, and it is necessary to use appropriate bioma...
Made available in DSpace on 2020-12-12T02:46:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Objective: The aim of this study was to evaluate the expression of DNA repair genes in cases of oral squamous cell carcinoma (OSCC). Study Design: Expression of the MLH1, MSH2, MLH3, ATM, MRE11A, XRCC1, and PMS2 genes was evaluated by reverse transcription–quantitative polymerase chain reaction in the O...
Made available in DSpace on 2020-12-12T02:17:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-15; In the oral cavity, Candida species form mixed biofilms with Streptococcus mutans, a pathogenic bacterium that can secrete quorum sensing molecules with antifungal activity. In this study, we extracted and fractioned culture filtrate of S. mutans, seeking antifungal agents capable of inhibiting the biof...
Made available in DSpace on 2020-12-12T02:20:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Candida auris has emerged as a medically important pathogen with considerable resistance to antifungal agents. The ability to produce biofilms is an important pathogenicity feature of this species that aids escape of host immune responses and antimicrobial agents. The objective of this study was to veri...