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In vitro metabolism of copalic and kaurenoic acids in rat and human liver micro...
Mauro, Mariana [UNESP]; da Silva, Rodrigo Moreira; de Campos, Michel Leandro; Bauermeister, Anelize; Lopes, Norberto PeporineMade available in DSpace on 2022-04-29T08:32:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Copalic (CA) and kaurenoic (KA) acids are the main diterpenes found in the oleoresin extracted from the copaiba tree (Copaifera sp). This study aimed to characterize the metabolism of CA and KA in rat and human liver microsomes using liquid chromatography with tandem mass spectrometry (LC-MS/MS). The in...
In vivo and in vitro anti-inflammatory and pro-osteogenic effects of citrus cys...
Leguizamón, Natalia Da Ponte [UNESP]; Rodrigues, Elisandra Marcia [UNESP]; de Campos, Michel Leandro; Nogueira, Andressa Vilas Boas [UNESP]Made available in DSpace on 2019-10-06T16:35:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-11-01; ASCRS Research Foundation; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Cystatins are natural inhibitors of cysteine peptidases. Recently, cystatin...
Design, synthesis and pharmacological evaluation of CVIB, a codrug of carvacrol...
de Oliveira Pedrosa Rolim, Michelle; de Almeida, Anderson Rodrigues; da Rocha Pitta, Maira Galdino; de Melo Rêgo, Moacyr Jesus BarretoMade available in DSpace on 2019-10-06T16:45:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-11-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Financiadora de Estudos e Projetos; The search for new drugs with anti-inflammatory properties remains a challenge for modern medicine. Among the various strategies ...