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The role of single-nucleotide polymorphism (SNPs) in toxicity of induction chem...

De Marchi, Pedro; Melendez, Matias E.; Laus, Ana C.; Kuhlmann, Pamela A.; de Carvalho, Ana Carolina; Arantes, Lidia Maria R.B.; Evangelista, Adriane F.

Made available in DSpace on 2022-04-28T19:27:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-11-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background: Induction chemotherapy in locally-advanced head and neck squamous cell carcinoma (LAHNSCC) patients is potentially associated to serious adverse events. Biomarkers associated with toxicity could tailor its indication. This...

Date: 2022   |   Origin: Oasisbr

Microbiota profile and impact of fusobacterium nucleatum in colorectal cancer p...

de Carvalho, Ana Carolina; de Mattos Pereira, Leandro; Datorre, José Guilherme; Dos Santos, Wellington; Berardinelli, Gustavo Noriz

Microbial diversity has been pointed out as a major factor in the development and progression of colorectal cancer (CRC). We sought to explore the richness and abundance of the microbial community of a series of colorectal tumor samples treated at Barretos Cancer Hospital, Brazil, through 16S rRNA sequencing. The presence and the impact of Fusobacterium nucleatum (Fn) DNA in CRC prognosis was further evaluated ...


Methylation of the hsa-miR-124, SOX1, TERT, and LMX1A genes as biomarkers for p...

Rogeri, Caroline Domingues; Silveira, Henrique César Santejo; Causin, Rhafaela Lima; Villa, Luisa Lina; Stein, Maíra Degiovani

The methylation profile of genes in precursor lesions in cervical cancer was characterized to improve screening techniques for high-grade intraepithelial neoplasia.


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