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Endometrial Cancer Spheres Show Cancer Stem Cells Phenotype and Preference for ...

Carvalho, MJ; Laranjo, M; Abrantes, AM; Casalta-Lopes, J; Sarmento-Santos, D; Costa, T; Serambeque, B; Almeida, N; Gonçalves, T; Mamede, C

This study aimed to characterize endometrial cancer regarding cancer stem cells (CSC) markers, regulatory and differentiation pathways, tumorigenicity and glucose metabolism. Endometrial cancer cell line ECC1 was submitted to sphere forming protocols. The first spheres generation (ES1) was cultured in adherent conditions (G1). This procedure was repeated and was obtained generations of spheres (ES1, ES2 and ES3...


Systemic lupus erythematosus in the elderly.

Sousa, C A; Baptista, I; Aguiar, P; Gonçalves, A; Cocco, C; de Carvalho, R

The authors report two clinical cases of systemic lupus erythematosus, both in patients over 65 years of age. The discussion includes a brief overview of recent publications on this condition in geriatric patients. Some aspects of systemic lupus in elderly persons are suggested and commented on.; The authors report two clinical cases of systemic lupus erythematosus, both in patients over 65 years of age. The di...

Date: 1995   |   Origin: Acta Médica Portuguesa

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