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O papel do farmacêutico no controle, orientação e prevenção da automedicação em...
Moysés, Daniele de Araújo; Galucio, Natasha Costa da Rocha; Silva, Ana Martha do Nascimento; Rocha, Andreza Abreu; Costa, Joseneide Gonçalves daFoi realizada uma Revisão da Literatura nos períodos de 2011 a 2021 por meio de Pesquisa Bibliográfica visando atualização do estado da arte sobre automedicação da população idosa e a atuação do farmacêutico. A pesquisa foi realizada nas bases de dados PubMed/Medline, SciELO, LILACS e Google Scholar, utilizando os seguintes descritores de saúde: automedicação, autoadministração, efeitos adversos, hábitos de con...
Antimalarial potential of quinones isolated from plants: an integrative review
Gomes, Antonio Rafael Quadros; Brígido, Heliton Patrick Cordovil; Vale, Valdicley Vieira; Correa-Barbosa, Juliana; Percário, SandroAntimalarial treatment is often associated with the resistance developed by Plasmodium which generate ineffective drug treatment. Based on this, the search for therapeutic alternatives is necessary and urgent. This review intends to assess the antimalarial potential of quinones isolated from plants. The search for scientific articles was carried out on the CAPES Journal Portal (PPC), Virtual Health Library (VHL...
Evaluation of potential drug interactions in prescriptions of antimicrobials in...
Vilaça, Samara de Oliveira; Santana, Diego da Silva; Alves, Elizama da Sá; Penha, Soraia dos Santos; Vale, Valdicley VieiraObjective: to evaluate the potential drug interactions of antimicrobials in prescriptions of patients admitted to a hospital in the State of Pará, in 2019. Methodology: This is a qualitative-quantitative, retrospective and cross-sectional study, carried out by collecting data from medical records of patients who used antibiotics and were hospitalized in 2019 in a hospital in Pará. Drug interactions were assesse...
Anti-malarial activity and toxicity of Aspidosperma nitidum Benth: a plant used...
Brandão, Dayse Lucia do Nascimento; Martins, Michel Tavares; Silva, Adreanne Oliveira; Almeida, Amanda Dias; Paula, Renata Cristina deThe objective of this work was to evaluate the antiplasmodial activity and toxicity of the extract and fractions obtained from the bark of Aspidosperma nitidum. The ethanol extract obtained from the powdered bark of plants was acid-base partitioned and phytochemically analyzed. The antiplasmodial activity, in vivo antimalarial activity and in vitro cytotoxicity were acessed. The selectivity index (SI) was calcu...
Antitumor activity of Apocynaceae species used in Amazon traditional medicine
Bastos, Mirian Letícia Carmo; Sarmento, Rosana Moura; Bahia, Marcelo de Oliveira; Rodrigues, Jaqueline da Silva; Vale, Valdicley VieiraThis study reviews the use of Apocynaceae species for cancer and tumor treatment in the Amazon. Databases and books were searched for ethnobotanical and phytochemical evaluations of the cytotoxic and anticancer activities of Apocynaceae species. The literature reports the use of several Amazonian species, such as Asclepias curassavica, Himatanthus articulates, and Macoubea sprucei, in treating tumors and cancer...
Naphthoquinones isolated from Eleutherine plicata herb: in vitro antimalarial a...
Vale, Valdicley Vieira; Cruz, Jorddy Neves; Viana, Giselle Maria Rachid; P?voa, Marinete Marins; Brasil, Davi do Socorro Barros; Dolabela, Maria FaniCAPES; CNPq; Universidade Federal do Par?. Instituto Ci?ncias da Sa?de. Programa de P?s-Gradua??o em Inova??o Farmac?utica. Bel?m, PA, Brazil.; Universidade Federal do Par?. Instituto de Tecnologia. Bel?m, PA, Brazil.; Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.; Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananin...
Anti-promastigote activity of the amazon plants
Silva-Silva, Jo?o Victor; Monteiro, R. C. S.; Brigido, H. P. C.; Vale, Valdicley Vieira; Silvestre, J. V.; Silva, N. C. S.; Silveira, Fernando TobiasUniversidade Federal do Par?. Programa de P?s-Gradua??o em Ci?ncias Farmac?uticas. Bel?m, PA, Brasil.; Universidade Federal do Par?. Programa de P?s-Gradua??o em Ci?ncias Farmac?uticas. Bel?m, PA, Brasil.; Universidade Federal do Par?. Programa de P?s-Gradua??o em Ci?ncias Farmac?uticas. Bel?m, PA, Brasil.; Universidade Federal do Par?. Programa de P?s-Gradua??o em Inova??o Farmac?utica. Bel?m, PA, Brasil.; Uni...
Anti-malarial activity and toxicity assessment of Himatanthus articulatus, a pl...
Vale, Valdicley Vieira; Vilhena, Thyago da Costa; Trindade, Rafaela Cabral dos Santos; Ferreira, Márlia Regina C.; Percário, SandroBackground: Plasmodium falciparum has become resistant to some of the available drugs. Several plant species are used for the treatment of malaria, such as Himatanthus articulatus in parts of Brazil. The present paper reports the phyto-chemistry, the anti-plasmodial and anti-malarial activity, as well as the toxicity of H. articulatus. Methods: Ethanol and dichloromethane extracts were obtained from the powder ...