19 documents found, page 1 of 2

Therapeutic potential of vanadium complexes with 1,10-phenanthroline ligands, q...

(VO)-O-IV-complexes formulated as [(VO)-O-IV(OSO3)(phen)(2)] (1) (phen = 1,10-phenanthroline), [(VO)-O-IV(OSO3) (Me(2)phen)(2)] (2) (Me(2)phen = 4,7-dimethyl-1,10-phenanthroline) and [(VO)-O-IV(OSO3)(amphen)(2)] (3) (amphen = 5-amino-1,10-phenanthroline) were prepared and stability in cell incubation media evaluated. Their cytotoxicity was determined against the A2780 (ovarian), MCF7 (breast) and PC3 (prostate)...

A new family of iron(II)-cyclopentadienyl compounds shows strong activity again...

A family of compounds with the general formula [Fe(η⁵-C₅H₅)(CO)(PPh₃)(NCR)]⁺ has been synthesized (NCR = benzonitrile (<b>1</b>); 4-hydroxybenzonitrile (<b>2</b>); 4-hydroxymethylbenzonitrile (<b>3</b>); 4-aminobenzonitrile (<b>4</b>); 4-bromobenzonitrile (<b>5</b>); and, 4-chlorocinnamonitrile (<b>6</b>)). All of the compounds were obtained in good yields ...

Methyl-cyclopentadienyl Ruthenium Compounds with 2,2'-Bipyridine Derivatives Di...

Ruthenium-cyclopentadienyl bipyridine-biotin based compounds: Synthesis and bio...

Prospective anticancer metallodrugs should consider target-specific components in their design in order to overcome the limitations of the current chemotherapeutics. The inclusion of vitamins, which receptors are overexpressed in many cancer cell lines, has proven to be a valid strategy. Therefore, in this paper we report the synthesis and characterization of a set of new compounds [Ru(eta(5)-C5H5)(P(C6H4R)(3))...

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorina...

Three new compounds have been synthesized and completely characterized by analytical and spectroscopic techniques. The new bipyridine-perfluorinated ligand L1 and the new organometallic complex [Ru(η 5 -MeCp)(PPh 3 ) 2 Cl] (Ru1) crystalize in the centrosymmetric triclinic space group P1¯. Analysis of the phenotypic effects induced by both organometallic complexes Ru1 and [Ru(η 5 -MeCp)(PPh 3 )(L1)][CF 3 SO 3 ] ...

Methyl-cyclopentadienyl ruthenium compounds with 2,2 '-bipyridine derivatives d...

New ruthenium methyl-cyclopentadienyl compounds bearing bipyridine derivatives with the general formula [Ru(eta(5)-MeCp)(PPh3)(4,4'-R-2,2'-bpy)](+) (Ru1, R = H; Ru2, R = CH3; and Ru3, R = CH2OH) have been synthesized and characterized by spectroscopic and analytical techniques. Ru1 crystallized in the monoclinic P2(1)/c, Ru2 in the triclinic P (1) over bar, and Ru3 in the monoclinic P2(1)/n space group. In all ...

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorina...

Three new compounds have been synthesized and completely characterized by analytical and spectroscopic techniques. The new bipyridine-perfluorinated ligand L1 and the new organometallic complex [Ru(eta(5)-MeCp)(PPh3)(2)Cl] (Ru1) crystalize in the centrosymmetric triclinic space group P (1) over bar. Analysis of the phenotypic effects induced by both organometallic complexes Ru1 and [Ru(eta(5)-MeCp)(PPh3)(L1)] [...

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorina...

Three new compounds have been synthesized and completely characterized by analytical and spectroscopic techniques. The new bipyridine-perfluorinated ligand L1 and the new organometallic complex [Ru(η5-MeCp)(PPh3)2Cl] (Ru1) crystalize in the centrosymmetric triclinic space group P <img height="13" border="0" style="vertical-align:bottom" width="11" alt="View the MathML source" title="View the MathML source" src=...

New Cu(II) complexes with pyrazolyl derived schiff base ligands: synthesis and ...

Since the discovery of cisplatin there has been a continuous pursuit for new metallodrugs showing higher efficacies and lower side effects. In this work, new copper(II) complexes (C1-C6) of Schiff bases derived from pyrazolyl were developed. Through condensation of 5-methyl-1H-pyrazole-3-carbohydrazide with different aromatic aldehydes - pyridoxal, salicylaldehyde, 3-methoxy-2-hydroxybenzaldehyde, 3-ethoxy-2-hy...

η6-(2-phenoxyethanol) ruthenium(II)-complexes of 2,2′-bipyridine and its deriva...

A novel family of Ru-II-arene compounds with the general formula of [Ru-II(eta(6)-(2-phenoxyethanol))(L) Cl](+) (L: 2,2'-bipyridine (bpy) (3), 4,4'-dimethyl-2,2'-bipyridine (4) and 4,4'-diyldimethanol-2,2'-bipyridine (5)) was synthesized and characterized by standard spectroscopic and analytical methods. Complex 3 was further studied by single-crystal X-ray diffraction analysis, showing a pseudo octahedral geom...