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The Dynamics of the Pulmonary Microbiome During Mechanical Ventilation in the I...

Zakharkina, T; Martin-Loeches, I; Matamoros, S; Povoa, P; Torres, A; Kastelijn, JB; Hofstra, JJ; de Wever, B; de Jong, M; Schultz, MJ; Sterk, PJ

RATIONALE: Ventilator-associated pneumonia (VAP) is the most common nosocomial infections in patients admitted to the ICU. The adapted island model predicts several changes in the respiratory microbiome during intubation and mechanical ventilation. OBJECTIVES: We hypothesised that mechanical ventilation and antibiotic administration decrease the diversity of the respiratory microbiome and that these changes are...

Date: 2017   |   Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
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