Made available in DSpace on 2022-04-29T08:38:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; ASCRS Research Foundation; This study evaluated the in vitro modulatory effect of vitamin D (VD) on T cells, by determining the expression of STATs and the transcription factors of each CD4+ T cell subsets. Twenty women with preeclampsia (PE) and 20 normotensive pregnant women were studied. Peripheral b...
Made available in DSpace on 2022-05-01T11:54:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; This study evaluated the impact of vitamin D on Human Umbilical Vein Endothelial Cells (HUVEC) and inflammation in placental explants from women with preeclampsia (PE). HUVEC and explants from 10 late-onset PE (LOPE), 10 early-onset (EOPE), and 10 normotensive (NT) pregnant women were cultured with/with...
Made available in DSpace on 2022-04-29T02:55:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-01-01; The aim of the present study was to investigate the presence of Trypanosoma cruzi in the heart, liver, lung, and kidneys, using hemoculture and PCR analysis, of mice infected with different parasite strains during the acute and chronic phases of infection. Parasitemia curves revealed strain-specific bio...
Made available in DSpace on 2021-06-25T10:44:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-30; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (CNS). The persistent inflammation is being mainly attributed to local oxidative stress and inflammasome activation implicated in the ensuing ...
Made available in DSpace on 2021-06-25T11:08:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Multiple sclerosis is an autoimmune disease that affects the myelinated central nervous system (CNS) n...
Made available in DSpace on 2020-12-12T02:01:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-03-12; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Multiple sclerosis (MS) is a progressive disease of the central nervous system (CNS) that involves damage to the myelin sheath surrounding axons. MS therapy is based on im...
Made available in DSpace on 2019-10-06T16:46:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01; Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by extensive inflammation, demyelination, axonal loss and gliosis. Evidence indicates that mast cells contribute to immunopathogenesis of both MS and experimental autoimmune encephalomyelitis (EAE),...