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In Vitro Antimicrobial Studies of Mesoporous Silica Nanoparticles Comprising An...

Filipe, Luís; de Sousa, Telma; Silva, Dário; Santos, Miguel M.; Ribeiro Carrott, Manuela; Poeta, Patrícia; Branco, Luís C.; Gago, Sandra

Funding Information: The NMR spectrometers are part of the National NMR Network (PTNMR) and are partially supported by Infrastructure Project N° 022161 (co-financed by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC). Funding Information: The authors LF and TdS thank FCT/MCTES (Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) for PhD grants ref. DFA/...


Study of Antimicrobial Resistance, Biofilm Formation, and Motility of Pseudomon...

de Sousa, Telma; Hébraud, Michel; Alves, Olimpia; Costa, Eliana; Maltez, Luís; Pereira, José Eduardo; Martins, Ângela; Igrejas, Gilberto

Funding Information: This research was funded by FCT (Fundação para a Ciência e a Tecnologia) related to a PhD grant, through the reference DFA/BD/5332/2020. Publisher Copyright: © 2023 by the authors.; Pseudomonas aeruginosa causes urinary tract infections associated with catheters by forming biofilms on the surface of indwelling catheters. Therefore, controlling the spread of the bacteria is crucial to preven...


The Impact of the Virulence of Pseudomonas aeruginosa Isolated from Dogs

de Sousa, Telma; Garcês, Andreia; Silva, Augusto; Lopes, Ricardo; Alegria, Nuno; Hébraud, Michel; Igrejas, Gilberto; Poeta, Patricia

Funding Information: This research was funded by FCT (Fundação para a Ciência e a Tecnologia) related to PhD grant, through the reference DFA/BD/5332/2020. Publisher Copyright: © 2023 by the authors.; Pseudomonas aeruginosa is a pathogenic bacterium that can cause serious infections in both humans and animals, including dogs. Treatment of this bacterium is challenging because some strains have developed multi-d...


The 10,000-year success story of wheat!

de Sousa, Telma; Ribeiro, Miguel; Sabença, Carolina; Igrejas, Gilberto

POCI-01-0145-FEDER-029068; Wheat is one of the most important cereal crops in the world as it is used in the production of a diverse range of traditional and modern processed foods. The ancient varieties einkorn, emmer, and spelt not only played an important role as a source of food but became the ancestors of the modern varieties currently grown worldwide. Hexaploid wheat (Triticum aestivum L.) and tetraploid ...


Putative protein biomarkers of escherichia coli antibiotic multiresistance iden...

de Sousa, Telma; Viala, Didier; Théron, Laetitia; Chambon, Christophe; Hébraud, Michel; Poeta, Patricia; Igrejas, Gilberto

Ação n.º: TC-14/2017 UIDB/50006/2020; The commensal bacteria Escherichia coli causes several intestinal and extra-intestinal diseases, since it has virulence factors that interfere in important cellular processes. These bacteria also have a great capacity to spread the resistance genes, sometimes to phylogenetically distant bacteria, which poses an additional threat to public health worldwide. Here, we aimed to...


Next-generation sequencing and maldi mass spectrometry in the study of multires...

Sabença, Carolina; de Sousa, Telma; Oliveira, Soraia; Viala, Didier; Théron, Laetitia; Chambon, Christophe; Hébraud, Michel; Beyrouthy, Racha

Ação n.º: TC-14 / 2017 UID/QUI/50006/2020 UIDB/00211/2020 UMR1071 USC-2018; Vancomycin-resistant enterococci (VRE), due to their intrinsic resistance to various commonly used antibiotics and their malleable genome, make the treatment of infections caused by these bacteria less effective. The aims of this work were to characterize isolates of Enterococcus spp. that originated from processed meat, through phenoty...


Review of structural features and binding capacity of polyphenols to gluten pro...

Ribeiro, Miguel; de Sousa, Telma; Poeta, Patrícia; Bagulho, Ana Sofia; Igrejas, Gilberto

UIDB 50006/2020 UID/AGR/04033/2019 project-POCI-01-0145-FEDER-029068; Polyphenols have been extensively studied due to their beneficial effects on human health, particularly for the prevention and treatment of diseases related to oxidative stress. Nevertheless, they are also known to have an anti-nutritional effect in relation to protein metabolism. This effect is a consequence of its binding to digestive enzym...


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