2 documents found, page 1 of 1
Extracellular vesicle transfer of lncRNA H19 splice variants to cardiac cells
Vilaça, Andreia; Jesus, Carlos; Lino, Miguel; Hayman, Danika; Emanueli, Costanza; Terracciano, Cesare M.; Fernandes, Hugo; de Windt, Leon J.CC BY-NC-ND 4.0; The authors would like to acknowledge Crioestaminal (www.crioestaminal.pt) for providing samples and other helpful information and Dr. Yingqun Huang for providing the lncRNA H19 plasmid. The authors would further like to acknowledge the funding by the FCT PhD Studentships (SFRH/BD/119187/2016 & SFRH/BD/ 144092/2019), Programa Operacional Competividade e Internacionalização (POCI) na sua compone...
MicroRNA-216a is essential for cardiac angiogenesis
Juni, Rio P.; Kocken, Jordy M. M.; Abreu, Ricardo C.; Ottaviani, Lara; Davalan, Tim; Duygu, Burcu; Poels, Ella M.; Vasilevich, AliakseiWhile it is experimentally supported that impaired myocardial vascularization contributes to a mismatch between myocardial oxygen demand and supply, a mechanistic basis for disruption of coordinated tissue growth and angiogenesis in heart failure remains poorly understood. Silencing strategies that impair microRNA biogenesis have firmly implicated microRNAs in the regulation of angiogenesis, and individual micr...