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CuMV VLPs Containing the RBM from SARS-CoV-2 Spike Protein Drive Dendritic Cell...

Sebastião, Ana Isabel; Mateus, Daniela; Carrascal, Mylène A.; Sousa, Cátia; Cortes, Luísa; Bachmann, Martin F; do Carmo, Anália; Matos, Ana M.

Dendritic cells (DCs) are the most specialized and proficient antigen-presenting cells. They bridge innate and adaptive immunity and display a powerful capacity to prime antigen-specific T cells. The interaction of DCs with the receptor-binding domain of the spike (S) protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pivotal step to induce effective immunity against the S protei...


Evaluation of the Effect of Hemoglobin Concentration and of Mean Corpuscular Vo...

do Carmo, Anália; Queiroz, Ana Carolina; Escada Fontes, Fernanda; Mariano Pego, João; Tomé, Rui; Rodrigues, Fernando

Introduction: Diabetes mellitus (DM) is a metabolic disordercharacterized by chronic hyperglycemia and by the developmentof serious complications which determine the loss of thepatient’s quality of life. The evaluation of the glycemic controlin diabetic patients can be made based on the glycatedhemoglobin A1c (HbA1c) value. However, several studiesreported that anemia may limit the determination of HbA1c.Theref...


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