6 documents found, page 1 of 1
Dent disease: A cause of proteinuria against all odds
Rosinha, Inês; Machado, Marta; Cordinhã, Carolina; do Carmo, Carmen; Gomes, ClaraDent disease is a rare X-linked progressive renal disease characterized by hypercalciuria and low molecular weight proteinuria. In early childhood, patients may manifest only proteinuria and/or hypercalciuria, both of which are generally asymptomatic. The authors report three cases of male patients with asymptomatic, non-orthostatic nephrotic proteinuria first detected during screening for an acute condition. A...
Clinical Presentation and Treatment of Childhood‐Onset Lupus Nephritis
Silva, Rita M.; Correia , Ana L.; Marques, Maria G.; Cordinhã, Carolina; Romãozinho, Catarina; Oliveira, Nuno A.; do Carmo, Carmen; Gomes, ClaraIntroduction: Lupus nephritis (LN) in childhood usually presents after the age of 10 years and is more common in female children. Despite the availability of effective immunosuppressive therapies, treatment response in childhood‐onset LN remains suboptimal, with 50% to 78% patients in full remission at 24 months. Improvement in survivals have also plateaued in past decades, and up to 9% and 14% of children with...
Cystic Kidney Disease: An Early Manifestation of a Rare Syndrome
Leuzinger-Dias, Catarina; P. Ramos, Joana; Machado, Marta; Cordinhã, Carolina; do Carmo, Carmen; Gomes, ClaraPediatric cystic kidney diseases include a diversity of hereditary or non‐hereditary conditions, whose phenotypic presen‐ tation can vary from asymptomatic to end‐stage renal disease. We report a case of a male with a prenatal diagnosis of pyelectasis. Throughout the first two years of life, serial renal ultrasound showed regression of pyelectasis, but increased renal echogenicity, first identified at three mon...
Spondylodiscitis and epidural abscess - two clinical cases
Grebe, Hans Peter; Ferreira, Paulo; do Carmo, Carmen; Rodrigues, Adriano; Almiro, EuricoSpondylodiscitis and spinal epidural abscesses are rare pathologic entities, but increasing in incidence. They often present clinically in a non-specific fashion, a fact which can Jead to diagnostic delay, with serious consequences for the patient. A high levei of suspicion is therefore necessary in order correctly diagnose such entities as quickly as possible. A patient with otherwise unexplained spinal pain s...
Dent disease: A cause of proteinuria against all odds
Rosinha, Inês; Machado, Marta; Cordinhã, Carolina; do Carmo, Carmen; Gomes, ClaraDent disease is a rare X-linked progressive renal disease characterized by hypercalciuria and low molecular weight proteinuria. In early childhood, patients may manifest only proteinuria and/or hypercalciuria, both of which are generally asymptomatic. The authors report three cases of male patients with asymptomatic, non-orthostatic nephrotic proteinuria first detected during screening for an acute condition. A...
Posterior Urethral Valves: Experience of a Level III Hospital
Almeida, Sónia; Cascais, Mafalda; Cordinha, Carolina; do Carmo, Carmen; Gomes, Clara; Coutinho, Sílvia; Ramos, Manuel; Correia, A. JorgeIntroduction: The posterior urethral valves (PUV) are an important cause of congenital urinary tract obstruction affecting male children. Our aim in this study was to characterize the evolution of a children group with PUV with identification of possible risk factors to chronic kidney disease (CKD). Methods: Retrospective analysis of PUV children diagnosed between January 1999 and January 2017 in a level III ho...