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Inhibition of gelatinase activity of MMP-2 and MMP-9 by extracts of Bauhinia un...

dos Santos, Kamilla Monteiro; Nunes, Damiana Antônia de Fátima; Gomes, Izabela Natália Faria; da Silva, Saulo Luis

Metastasis is responsible for the majority of cancer-related deaths. Tumour invasion and metastasis result from processes that include the proteolytic degradation of the extracellular matrix adjacent to the tumour. The matrix metalloproteinases (MMPs), particularly MMP-2 and MMP-9, have prognostic influence in human cancers after they cleave the main structural components of the basal membrane. These actions ma...

Date: 2014   |   Origin: Oasisbr

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