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A parallel increase in placental oxidative stress and antioxidant defenses occu...

Araujo, JR; ramalho, c; Correia Branco, A; Faria, A; Ferraz, T; Keating, E; Martel, F

We aimed to determine the oxidative stress status in placentas obtained from gestational (GDM) and type 1 (T1D) diabetic pregnancies. Malonaldehyde and protein carbonyls, two biomarkers of oxidative damage, were higher in T1D but not in GDM placentas. Also, higher reduced glutathione and lower oxidized glutathione levels and higher glutathione peroxidase activity were found in T1D but not in GDM placentas. Thes...


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